Primary aldosteronism (PA), the most common form of secondary hypertension, can be
either surgically cured or treated with targeted pharmacotherapy. PA is frequently …

Primary aldosteronism is characterized by aldosterone secretion that is independent of renin
and angiotensin II and sodium status. The deleterious effects of primary aldosteronism are …

Autonomous aldosterone overproduction represents the underlying condition of 5–10% of
patients with arterial hypertension and carries a significant burden of mortality and morbidity …

Early diagnosis and appropriate treatment of primary aldosteronism, the most frequent
cause of secondary hypertension, are crucial to prevent deleterious cardiovascular …

Among the ten subtypes of mammalian voltage-gated calcium (Ca v) channels, Ca v 3.1–Ca
v 3.3 constitute the T-type, or the low-voltage-activated, subfamily, the abnormal activities of …

Aldosterone-producing adenomas (APAs) are the commonest curable cause of
hypertension. Most have gain-of-function somatic mutations of ion channels or transporters …

Primary aldosteronism is the most common and curable form of secondary arterial
hypertension. We performed whole-exome sequencing in patients with early-onset primary …

Primary aldosteronism is considered the commonest cause of secondary hypertension. In
affected individuals, aldosterone is produced in an at least partially autonomous fashion in …

The syndrome of primary aldosteronism (PA) is characterized by hypertension with
excessive, autonomous aldosterone production and is usually caused by either a unilateral …

Aldosterone-producing adenoma (APA) cause primary aldosteronism—the most frequent
form of secondary hypertension. Somatic mutations in genes coding for ion channels and …