ApoE is the major lipid and cholesterol carrier in the CNS. There are three major human
polymorphisms, apoE2, apoE3, and apoE4, and the genetic expression of APOE4 is one of …

The goal of this article is to provide a general review of the epidemiology, acute care, and
chronic management of adult patients with traumatic brain injuries (TBI). This text was …

Research into TBI biomarkers has accelerated rapidly in the past decade owing to the
heterogeneous nature of TBI pathologies and management, which pose challenges to TBI …

Cathepsin B (CTSB) is a powerful lysosomal protease. This review evaluated CTSB gene
knockout (KO) outcomes for amelioration of brain dysfunctions in neurologic diseases and …

Abstract VISSER, K., M. Koggel, J. Blaauw, HJvd Horn, B. Jacobs, and Jvd Naalt. Blood
based biomarkers of inflammation in mild traumatic brain injury: A systematic review …

Acquired traumatic brain injury (TBI) is frequently accompanied by persistent cognitive
symptoms, including executive function disruptions and memory deficits. The Morris Water …

Traumatic brain injury (TBI) is distinct from other neurological disorders because it is
induced by a discrete event that applies extreme mechanical forces to the brain. This review …

Traumatic brain injury (TBI) is a major cause of death and disability. Despite its importance
in public health, there are presently no drugs to treat TBI. Many reasons underlie why drugs …

Post-traumatic epilepsy (PTE) is one of the most devastating long-term, network
consequences of traumatic brain injury (TBI). There is currently no approved treatment that …

Traumatic brain injury (TBI) is one of the most prevalent causes of permanent physical and
cognitive disabilities. TBI pathology results from primary insults and a multi‐mechanistic …