Ror‐family receptor tyrosine kinases in noncanonical Wnt signaling: Their implications in developmental morphogenesis and human diseases

Y Minami, I Oishi, M Endo… - … dynamics: an official …, 2010 - Wiley Online Library
The Ror‐family receptor tyrosine kinases (RTKs) play crucial roles in the development of
various organs and tissues. In mammals, Ror2, a member of the Ror‐family RTKs, has been …

Initiating and growing an axon

F Polleux, W Snider - Cold Spring Harbor perspectives …, 2010 - cshperspectives.cshlp.org
The ability of neurons to form a single axon and multiple dendrites underlies the directional
flow of information transfer in the central nervous system. Dendrites and axons are …

The bright side of JNKs—multitalented mediators in neuronal sprouting, brain development and nerve fiber regeneration

V Waetzig, Y Zhao, T Herdegen - Progress in neurobiology, 2006 - Elsevier
The c-Jun N-terminal kinases (JNKs) are important regulators of physiological and
pathological processes in the central and peripheral nervous system. In general, JNKs are …

Wnt-3a and Dickkopf-1 stimulate neurite outgrowth in Ewing tumor cells via a Frizzled3-and c-Jun N-terminal kinase-dependent mechanism

Y Endo, E Beauchamp, D Woods… - … and cellular biology, 2008 - Am Soc Microbiol
Recombinant Wnt-3a stimulated the rapid formation of elongated processes in Ewing
sarcoma family tumor (ESFT) cells that were identified as neurites. The processes stained …

New therapeutic target for CNS injury? The role of retinoic acid signaling after nerve lesions

J Mey - Journal of neurobiology, 2006 - Wiley Online Library
Experiments with sciatic nerve lesions and spinal cord contusion injury demonstrate that the
retinoic acid (RA) signaling cascade is activated by these traumatic events. In both cases the …

Retinoic acid-dependent and-independent gene-regulatory pathways of Pitx3 in meso-diencephalic dopaminergic neurons

FMJ Jacobs, JV Veenvliet, WH Almirza… - …, 2011 - journals.biologists.com
Development of meso-diencephalic dopamine (mdDA) neurons requires the combined
actions of the orphan nuclear receptor Nurr1 and the paired-like homeobox transcription …

O-GlcNAcylation of tubulin inhibits its polymerization

S Ji, JG Kang, SY Park, JH Lee, YJ Oh, JW Cho - Amino acids, 2011 - Springer
The attachment of O-linked β-N-acetylglucosamine (O-GlcNAc) to proteins is an abundant
and reversible modification that involves many cellular processes including transcription …

Regulatory role of the JNK-STAT1/3 signaling in neuronal differentiation of cultured mouse embryonic stem cells

ZZ Wei, SP Yu, JH Lee, D Chen, TM Taylor… - Cellular and molecular …, 2014 - Springer
Stem cell transplantation therapy has provided promising hope for the treatment of a variety
of neurodegenerative disorders. Among challenges in developing disease-specific stem cell …

Arsenic exposure disrupts neurite growth and complexity in vitro

S Frankel, J Concannon, K Brusky, E Pietrowicz… - Neurotoxicology, 2009 - Elsevier
Arsenic has neurotoxic effects on both central and peripheral components of the mature
nervous system. There is increasing evidence that exposure to arsenic is also toxic to the …

Pulsed electromagnetic fields potentiate neurite outgrowth in the dopaminergic MN9D cell line

R Lekhraj, DE Cynamon, SE DeLuca… - Journal of …, 2014 - Wiley Online Library
Pulsed electromagnetic fields (PEMF) exert biological effects and are in clinical use to
facilitate bone repair and wound healing. Research has demonstrated that PEMF can …