Emerging methods in biomarker identification for extracellular vesicle‐based liquid biopsy

Y Liang, BM Lehrich, S Zheng… - Journal of Extracellular …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are released by many cell types and distributed within various
biofluids. EVs have a lipid membrane‐confined structure that allows for carrying unique …

Electrochemical nano biosensors for the detection of extracellular vesicles exosomes: From the benchtop to everywhere?

S Singh, A Numan, S Cinti - Biosensors and Bioelectronics, 2022 - Elsevier
Detection of extracellular vesicles (EVs) exosomes is a challenge to address the need for
better diagnostic tests and to create a point-of-care (POC) platform that can detect, monitor …

Rapid and unamplified identification of COVID-19 with morpholino-modified graphene field-effect transistor nanosensor

J Li, D Wu, Y Yu, T Li, K Li, MM Xiao, Y Li… - Biosensors and …, 2021 - Elsevier
SARS-CoV-2 RNA is identified as a pivotal player to bolster energizing zones of COVID-19
detection. Herein, we develop a rapid and unamplified nanosensing platform for detection of …

Simultaneous detection of tumor derived exosomal protein–microRNA pairs with an Exo-PROS biosensor for cancer diagnosis

CC Hsu, Y Yang, E Kannisto, X Zeng, G Yu… - ACS …, 2023 - ACS Publications
Tumor derived exosomes (TEXs) have emerged as promising biomarkers for cancer liquid
biopsy. Conventional methods (such as ELISA and qRT-PCR) and emerging biosensing …

Poly-l-Lysine-Modified Graphene Field-Effect Transistor Biosensors for Ultrasensitive Breast Cancer miRNAs and SARS-CoV-2 RNA Detection

J Gao, C Wang, C Wang, Y Chu, S Wang… - Analytical …, 2022 - ACS Publications
(Mi) RNAs are important biomarkers for cancers diagnosis and pandemic diseases, which
require fast, ultrasensitive, and economical detection strategies to quantitatively detect exact …

Microfluidic‐based exosome analysis for liquid biopsy

B Lin, Y Lei, J Wang, L Zhu, Y Wu, H Zhang… - Small …, 2021 - Wiley Online Library
Liquid biopsy offers non‐invasive and real‐time molecular profiling of individual patients,
and is thus considered a revolutionary technology in precision medicine. Exosomes have …

[HTML][HTML] Small extracellular vesicles in cancer

K Abhange, A Makler, Y Wen, N Ramnauth, W Mao… - Bioactive Materials, 2021 - Elsevier
Extracellular vesicles (EV) are lipid-bilayer enclosed vesicles in submicron size that are
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …

Electrochemical biosensors in exosome analysis; a short journey to the present and future trends in early-stage evaluation of cancers

E Dezhakam, B Khalilzadeh, M Mahdipour… - Biosensors and …, 2023 - Elsevier
The tumor microenvironment consists of a multiplicity of cells such as cancer cells,
fibroblasts, endothelial cells, and immune cells within the specific parenchyma. It has been …

Graphene-based field effect transistor biosensors for breast cancer detection: A review on biosensing strategies

I Novodchuk, M Bajcsy, M Yavuz - Carbon, 2021 - Elsevier
Breast cancer (BC) is the most occurring cancer in females and the second most commonly
occurring cancer world-wide. Early detection of BC may ease the treatment and prevent the …

Applications of graphene-based electrochemical and optical biosensors in early detection of cancer biomarkers

F Arshad, F Nabi, S Iqbal, RH Khan - Colloids and Surfaces B: Biointerfaces, 2022 - Elsevier
Graphene is a one-atom-thick carbon compound, which holds promises for detecting cancer
biomarkers along with its derivatives. The atom-wide graphene layer is ideal for cancer …