The ability of the complement system to rapidly and broadly react to microbial intruders,
apoptotic cells and other threats by inducing forceful elimination responses is indispensable …

Blood-contacting medical devices are an integral part of modern medicine. Such devices
may be used for only a few hours or may be implanted for life. Despite advances in …

Coagulation and innate immunity are linked evolutionary processes that orchestrate the host
defence against invading pathogens and injury. The complement system is integral to innate …

Combining stem cells with biomaterial scaffolds serves as a promising strategy for
engineering tissues for both in vitro and in vivo applications. This updated review details …

Significant advances have lead to a greater understanding of the role of the complement
system within nephrology. The success of the first clinically approved complement inhibitor …

Complement is one of the most ancient defense systems. It gets strongly activated
immediately after acute injuries like trauma, burn, or sepsis and helps to initiate …

The human plasma contact system is an immune surveillance system activated by the
negatively charged surfaces of bacteria and fungi and includes the kallikrein-kinin, the …

Considering the multifaceted protective and homeostatic roles of the complement system,
many consequences arise when drug carriers, and particulate pharmaceutical formulations …

Although several studies have evaluated the effects of Thallium (Tl) in adult species of fish,
the developmental toxicity of Tl has not been previously explored. In this study, zebrafish …

Sepsis as life‐threatening organ dysfunction caused by microorganisms represents a
dreadful challenge for the immune system. The role of the complement system as major …