Metabolites of microbiota response to tryptophan and intestinal mucosal immunity: A therapeutic target to control intestinal inflammation

J Zhang, S Zhu, N Ma, LJ Johnston… - Medicinal Research …, 2021 - Wiley Online Library
In a complex, diverse intestinal environment, commensal microbiota metabolizes excessive
dietary tryptophan to produce more bioactive metabolites connecting with kinds of diverse …

Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities

X Wu, Y Xia, F He, C Zhu, W Ren - Microbiome, 2021 - Springer
Bacteria, viruses, protozoa, and fungi establish a complex ecosystem in the gut. Like other
microbiota, gut mycobiota plays an indispensable role in modulating intestinal physiology …

Bidirectional gut-brain-microbiota axis as a potential link between inflammatory bowel disease and ischemic stroke

L Zhao, Q Xiong, CM Stary, OK Mahgoub, Y Ye… - Journal of …, 2018 - Springer
Emerging evidence suggests that gut-brain-microbiota axis (GBMAx) may play a pivotal role
linking gastrointestinal and neuronal disease. In this review, we summarize the latest …

Macrophage depletion alters bacterial gut microbiota partly through fungal overgrowth in feces that worsens cecal ligation and puncture sepsis mice

P Hiengrach, W Panpetch, A Chindamporn… - Scientific reports, 2022 - nature.com
Because macrophage dysfunction from some emerging therapies might worsen gut-derived
sepsis, cecal ligation and puncture (CLP) sepsis are performed in mice with clodronate …

From birth and throughout life: fungal microbiota in nutrition and metabolic health

WD Fiers, I Leonardi, ID Iliev - Annual review of nutrition, 2020 - annualreviews.org
The human gastrointestinal tract is home to a vibrant, diverse ecosystem of prokaryotic and
eukaryotic microorganisms. The gut fungi (mycobiota) have recently risen to prominence …

Resveratrol alleviates DSS-induced IBD in mice by regulating the intestinal microbiota-macrophage-arginine metabolism axis

X Xu, DKW Ocansey, B Pei, Y Zhang, N Wang… - European Journal of …, 2023 - Springer
Background Inflammatory bowel disease (IBD) is a global disease with a growing public
health concern and is associated with a complex interplay of factors, including the …

Artemisinin ameliorates intestinal inflammation by skewing macrophages to the M2 phenotype and inhibiting epithelial–mesenchymal transition

M Huai, J Zeng, W Ge - International Immunopharmacology, 2021 - Elsevier
Background Inflammatory bowel disease (IBD) is a self-destructive intestinal disease whose
etiology is unclear but complex and the effective treatment is deficient. Increasing evidences …

Unraveling the interconnection patterns across lung microbiome, respiratory diseases, and COVID-19

E Stavropoulou, K Kantartzi, C Tsigalou… - Frontiers in cellular …, 2021 - frontiersin.org
Albeit the lungs were thought to be sterile, recent scientific data reported a microbial
microbiota in the lungs of healthy individuals. Apparently, new developments in …

Candida spp. in Human Intestinal Health and Disease: More than a Gut Feeling

IAM Kreulen, WJ de Jonge, RM van den Wijngaard… - Mycopathologia, 2023 - Springer
Fungi are an essential part of the normal collection of intestinal microorganisms, even
though their collective abundance comprises only 0.1–1% of all fecal microbes. The …

Quercetin protects against Aspergillus fumigatus keratitis by reducing fungal load and inhibiting TLR-4 induced inflammatory response

J Luan, Y Zhu, J Lin, Y Zhang, Q Xu, L Zhan, X Tian… - Cytokine, 2023 - Elsevier
Purpose To investigate the antifungal and anti-inflammatory effects of quercetin in
Aspergillus fumigatus (A. fumigatus) keratitis. Methods Draize eye test was performed in …