Mitophagy is an essential mitochondrial quality control mechanism that eliminates damaged
mitochondria and the production of reactive oxygen species (ROS). The relationship …

In eukaryotic cells, macromolecular homeostasis requires selective degradation of damaged
units by the ubiquitin-proteasome system (UPS) and autophagy. Thus, dysfunctional …

Gastric cancer remains a major unmet clinical problem with over 1 million new cases
worldwide. It is the fourth most commonly occurring cancer in men and the seventh most …

Autophagy, as a type II programmed cell death, plays crucial roles with autophagy-related
(ATG) proteins in cancer. Up to now, the dual role of autophagy both in cancer progression …

Macroautophagy (hereafter referred to as autophagy) is an evolutionarily conserved cellular
process capable of degrading various biological molecules (eg, protein, glycogen, lipids …

Autophagy is the process by which cells degrade and recycle proteins and organelles to
maintain intracellular homeostasis. Generally, autophagy plays a protective role in cells, but …

Macroautophagy (hereafter referred to as autophagy) involves an intracellular degradation
and recycling system that, in a context-dependent manner, can either promote cell survival …

While glia are essential for regulating the homeostasis in the normal brain, their dysfunction
contributes to neurodegeneration in many brain diseases, including Parkinson's disease …

Autophagy is an intracellular catabolic pathway in which cellular constituents are engulfed
by autophagosomes and degraded upon autophagosome fusion with lysosomes …

Ferroptosis is a form of regulated cell death triggered by lipid peroxidation after inhibition of
the cystine/glutamate antiporter system X c–. However, key regulators of system X c–activity …