For inhalation drug delivery, amorphous powder formulations offer the benefits of increased
bioavailability for poorly soluble drugs, improved biochemical stability for biologics, and …

Powders for nasal delivery have been recognized as advantageous dosage forms over
liquids due to increased stability and residence time on nasal mucosa, with improved …

Purpose Inhalation therapy is popular to treat lower respiratory tract infections. Azithromycin
is effective against some bacteria that cause respiratory tract infections; but it has poor water …

Introduction: The number of pulmonary diseases that are effectively treated by aerosolized
medicine continues to grow. Areas covered: These diseases include chronic obstructive …

This study aimed to develop a dry powder inhaler (DPI) formulation for enhanced deep lung
delivery of rifampicin using dextrans of different molecular weights. Porous particles were …

The nose-to-brain delivery of ghrelin loaded in liposomes is a promising approach for the
management of cachexia. It could limit the plasmatic degradation of ghrelin and provide …

Pulmonary inflammations such as chronic obstructive pulmonary disease and cystic fibrosis
are widespread and can be fatal, especially when they are characterized by abnormal …

It is well established that currently available inhaled drug formulations are associated with
extremely low lung deposition. Currently available technologies alleviate this low deposition …

This systematic and comprehensive study reports for the first time on the successful rational
design of advanced inhalable therapeutic dry powders containing dimethyl fumarate, a first …

This work aims to identify a suitable formulation for the pulmonary delivery of combinations
of inhalational drugs using highly branched cyclic dextrin (HBCD) macromolecules. We …