Breakthroughs in hepatocellular carcinoma therapies

AG Singal, M Kudo, J Bruix - Clinical Gastroenterology and Hepatology, 2023 - Elsevier
Several breakthroughs in hepatocellular carcinoma (HCC) therapy across tumor stages
provide hope to improve its dismal prognosis. Although surgical and local ablative therapies …

Merits and boundaries of the Barcelona Clinic Liver Cancer Staging and Treatment Algorithm: learning from the past to improve the future with a novel proposal.

F Trevisani, A Vitale, M Kudo, L Kulik, JW Park… - Journal of …, 2024 - Elsevier
Summary This Expert Opinion article thoroughly analyses the Barcelona Clinic Liver Cancer
(BCLC) staging and treatment algorithm for hepatocellular carcinoma (HCC) that, since …

[HTML][HTML] Drug-off criteria in patients with hepatocellular carcinoma who achieved clinical complete response after combination immunotherapy combined with …

M Kudo - Liver cancer, 2023 - karger.com
Hepatocellular carcinoma (HCC) is refractory to treatment under the following conditions:(A)
a large number of tumors,(B) large tumor size,(C) vascular invasion or extrahepatic spread …

[PDF][PDF] Current therapeutic strategies for hepatocellular carcinoma in Japan

M Kudo - Liver cancer, 2023 - karger.com
The treatment outcomes of patients with hepatocellular carcinoma (HCC) in Japan have
improved dramatically over the past 40 years and are probably the best in the world …

All stages of hepatocellular carcinoma patients benefit from systemic therapy combined with locoregional therapy

M Kudo - Liver Cancer, 2023 - karger.com
Recent advances in systemic therapy for hepatocellular carcinoma (HCC) have been
remarkable. Systemic therapies were initially developed for advanced HCC. Today …

Clinical outcomes and histologic findings of patients with hepatocellular carcinoma with durable partial response or durable stable disease after receiving …

YC Shen, TH Liu, A Nicholas, A Soyama… - Journal of Clinical …, 2024 - ascopubs.org
PURPOSE Durable partial response (PR) and durable stable disease (SD) are often seen in
patients with hepatocellular carcinoma (HCC) receiving atezolizumab plus bevacizumab …

Advances in immunotherapy for hepatocellular carcinoma

S Hagiwara, N Nishida, M Kudo - Cancers, 2023 - mdpi.com
Simple Summary Immunotherapy for hepatocellular carcinoma (HCC) is progressing rapidly.
In particular, analyses of the tumor immune environment in HCC are progressing. Moreover …

Systemic therapies for hepatocellular carcinoma in India

V Jahagirdar, K Rama, MF Habeeb, M Sharma… - Journal of Clinical and …, 2024 - Elsevier
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality in India. This
review explores the epidemiological trends and the landscape of systemic therapy for HCC …

Clinical Complete Response After Conversion Therapy for Unresectable Hepatocellular Carcinoma: Is Salvage Hepatectomy Necessary?

JY Wu, JY Wu, DY Liu, H Li, SW Zhuang… - Journal of …, 2023 - Taylor & Francis
Background This study aimed to determine whether salvage hepatectomy offers prognostic
advantages for unresectable hepatocellular carcinoma (uHCC) patients with clinical …

Predictive factors for transition to conversion therapy in hepatocellular carcinoma using atezolizumab plus bevacizumab

T Kikuchi, Y Takeuchi, K Nouso, K Kariyama… - Liver …, 2024 - Wiley Online Library
Background To identify predictive factors associated with successful transition to conversion
therapy following combination therapy with atezolizumab and bevacizumab in the treatment …