Anoikis is a programmed cell death induced upon cell detachment from extracellular matrix,
behaving as a critical mechanism in preventing adherent-independent cell growth and …

Autophagy is a conserved process by which cytoplasmic components are degraded by the
lysosome. It is commonly seen as a cytoplasmic event and, until now, nuclear events were …

The BCL2 family plays important roles in acute myeloid leukemia (AML). Venetoclax, a
selective BCL2 inhibitor, has received FDA approval for the treatment of AML. However …

Macroautophagy (hereafter autophagy), literally defined as a type of self-eating, is a
dynamic cellular process in which cytoplasm is sequestered within a unique compartment …

Neddylation, a post-translational modification that conjugates an ubiquitin-like protein
NEDD8 to substrate proteins, is an important biochemical process that regulates protein …

Cancer constitutes a grave problem nowadays in view of the fact that it has become one of
the main causes of death worldwide. Poor clinical prognosis is presumably due to cancer …

Autophagy is an evolutionarily conserved process that promotes the lysosomal degradation
of intracellular components including organelles and portions of the cytoplasm. Besides …

Autophagy is a conserved catabolic process in eukaryotes that contributes to cell survival in
response to multiple stresses and is important for organism fitness. In Arabidopsis thaliana …

The endoplasmic reticulum (ER) is an elaborate organelle that is essential for cellular
function and survival. Conditions that interfere with ER functioning can lead to the …

Anti‐angiogenic therapy has increased the progression‐free survival of many cancer
patients but has had little effect on overall survival, even in colon cancer (average 6–8 …