Metabolomics and lipidomics in NAFLD: biomarkers and non-invasive diagnostic tests

M Masoodi, A Gastaldelli, T Hyötyläinen… - Nature reviews …, 2021 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases
worldwide and is often associated with aspects of metabolic syndrome. Despite its …

[HTML][HTML] An emerging focus on lipids in extracellular vesicles

T Skotland, K Sagini, K Sandvig, A Llorente - Advanced drug delivery …, 2020 - Elsevier
Extracellular vesicles contain a lipid bilayer membrane that protects the encapsulated
material, such as proteins, nucleic acids, lipids and metabolites, from the extracellular …

Lymph protects metastasizing melanoma cells from ferroptosis

JM Ubellacker, A Tasdogan, V Ramesh, B Shen… - Nature, 2020 - nature.com
Cancer cells, including melanoma cells, often metastasize regionally through the lymphatic
system before metastasizing systemically through the blood,,–; however, the reason for this …

A lipidome atlas in MS-DIAL 4

H Tsugawa, K Ikeda, M Takahashi, A Satoh… - Nature …, 2020 - nature.com
Abstract We present Mass Spectrometry-Data Independent Analysis software version 4 (MS-
DIAL 4), a comprehensive lipidome atlas with retention time, collision cross-section and …

Guidelines and considerations for the use of system suitability and quality control samples in mass spectrometry assays applied in untargeted clinical metabolomic …

D Broadhurst, R Goodacre, SN Reinke, J Kuligowski… - Metabolomics, 2018 - Springer
Background Quality assurance (QA) and quality control (QC) are two quality management
processes that are integral to the success of metabolomics including their application for the …

Lipidomics from sample preparation to data analysis: a primer

T Züllig, M Trötzmüller, HC Köfeler - Analytical and bioanalytical chemistry, 2020 - Springer
Lipids are amongst the most important organic compounds in living organisms, where they
serve as building blocks for cellular membranes as well as energy storage and signaling …

The foundations and development of lipidomics

X Han, RW Gross - Journal of lipid research, 2022 - ASBMB
For over a century, the importance of lipid metabolism in biology was recognized but difficult
to mechanistically understand due to the lack of sensitive and robust technologies for …

Ms-based lipidomics of human blood plasma: A community-initiated position paper to develop accepted guidelines1

B Burla, M Arita, M Arita, AK Bendt… - Journal of lipid …, 2018 - ASBMB
Human blood is a self-regenerating lipid-rich biological fluid that is routinely collected in
hospital settings. The inventory of lipid molecules found in blood plasma (plasma lipidome) …

Reference materials for MS-based untargeted metabolomics and lipidomics: a review by the metabolomics quality assurance and quality control consortium (mQACC)

KA Lippa, JJ Aristizabal-Henao, RD Beger, JA Bowden… - Metabolomics, 2022 - Springer
Introduction The metabolomics quality assurance and quality control consortium (mQACC) is
enabling the identification, development, prioritization, and promotion of suitable reference …

Recurrent topics in mass spectrometry-based metabolomics and lipidomics—standardization, coverage, and throughput

E Rampler, YE Abiead, H Schoeny, M Rusz… - Analytical …, 2020 - ACS Publications
We have come a long way in the last years of developing analytical strategies in
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …