Redox reactions are intrinsically linked to energy metabolism. Therefore, redox processes
are indispensable for organismal physiology and life itself. The term reactive oxygen species …

Abstract 'Reactive oxygen species'(ROS) is an umbrella term for an array of derivatives of
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …

While oxidases play crucial roles in the cell metabolism by efficient and selective utilization
of O 2, the practical applications of natural oxidases are limited due to their intrinsic …

Thioredoxin (Trx) and thioredoxin reductase (TrxR) are essential components of the Trx
system which plays pivotal roles in regulating multiple cellular redox signaling pathways. In …

Metastasis is the most frequent cause of death in cancer patients. Epithelial-to-mesenchymal
transition (EMT) is the process in which cells lose epithelial integrity and become motile, a …

Redox biology is at the core of life sciences, accompanied by the close correlation of redox
processes with biological activities. Redox homeostasis is a prerequisite for human health …

Lipid droplet formation is a defining histological feature in clear-cell renal cell carcinoma
(ccRCC) but the underlying mechanisms and importance of this biological behaviour have …

Metabolic alterations and elevated levels of reactive oxygen species (ROS) are two
characteristics of cancer. The metabolic patterns of cancer cells are elaborately …

The immune system is a crucial regulator of tumor biology with the capacity to support or
inhibit cancer development, growth, invasion and metastasis. Emerging evidence show that …

Significance: The p53 tumor suppressor has been dubbed the “guardian of genome”
because of its various roles in the response to DNA damage such as DNA damage repair …