Melatonin, an endogenously synthesized indolamine, is a powerful antioxidant exerting
beneficial action in many pathological conditions. Melatonin protects from oxidative stress in …

The tumor microenvironment (TME) includes a number of non-cancerous cells that affect
cancer cell survival. Although CD8+ T lymphocytes and natural killer (NK) cells suppress …

Recently, the morbidity and mortality from lung cancer have continued to increase.
Mitochondrial dysfunction plays a key role in apoptosis, proliferation, and the bioenergetic …

Melatonin is synthesized in the pineal gland at night. Since melatonin is produced in the
mitochondria of all other cells in a non-circadian manner, the amount synthesized by the …

The pineal gland-derived indoleamine hormone, melatonin, regulates multiple cellular
processes, ranging from chronobiology, proliferation, apoptosis, and oxidative damage to …

Glucose is an essential nutrient for every cell but its metabolic fate depends on cellular
phenotype. Normally, the product of cytosolic glycolysis, pyruvate, is transported into …

Introduction Melatonin, originally isolated from the mammalian pineal gland, was
subsequently identified in many animal cell types and in plants. While melatonin was …

Fighting infectious diseases, particularly viral infections, is a demanding task for human
health. Targeting the pathogens or targeting the host are different strategies, but with an …

Biomolecular condensates are membraneless organelles (MLOs) that form dynamic,
chemically distinct subcellular compartments organizing macromolecules such as proteins …

Melatonin is a neurohormone that is mainly secreted by the pineal gland. It coordinates the
work of the superior biological clock and consequently affects many processes in the human …