Curcumin activates the Nrf2 pathway and induces cellular protection against oxidative injury

M Ashrafizadeh, Z Ahmadi… - Current Molecular …, 2020 - ingentaconnect.com
Curcumin is a naturally occurring polyphenol that is isolated from the rhizome of Curcuma
longa (turmeric). This medicinal compound has different biological activities, including …

Curcumin production and bioavailability: A comprehensive review of curcumin extraction, synthesis, biotransformation and delivery systems

L Yixuan, MA Qaria, S Sivasamy, S Jianzhong… - Industrial Crops and …, 2021 - Elsevier
Curcuma longa, a perennial herb of the family genus turmeric, was used as a natural
pigment in the food industry in the ancient era. The medicinal efficacy and function of …

Engineering 4-coumaroyl-CoA derived polyketide production in Yarrowia lipolytica through a β-oxidation mediated strategy

CM Palmer, KK Miller, A Nguyen, HS Alper - Metabolic engineering, 2020 - Elsevier
Polyketides are a diverse class of molecules sought after for their valuable properties,
including as potential pharmaceuticals. Previously, we demonstrated that the oleaginous …

Endoplasmic reticulum stress in doxorubicin-induced cardiotoxicity may be therapeutically targeted by natural and chemical compounds: A review

F Yarmohammadi, R Rezaee, AW Haye… - Pharmacological …, 2021 - Elsevier
Doxorubicin (DOX) is a chemotherapeutic agent with marked, dose-dependent cardiotoxicity
that leads to tachycardia, atrial and ventricular arrhythmia, and irreversible heart failure …

[HTML][HTML] Liquid crystalline lipid nanoparticles for combined delivery of curcumin, fish oil and BDNF: In vitro neuroprotective potential in a cellular model of tunicamycin …

M Rakotoarisoa, B Angelov, M Drechsler… - Smart Materials in …, 2022 - Elsevier
We develop multidrug-loaded cubosome and spongosome lipid nanoparticles for targeting
of endoplasmic reticulum stress as a potential emerging therapeutic strategy against …

[HTML][HTML] Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways

D Liao, D Shangguan, Y Wu, Y Chen, N Liu, J Tang… - …, 2023 - Springer
Background Doxorubicin (DOX)-induced neurotoxicity is widely reported in previous studies.
Oxidative stress has been validated as a critical event involved in DOX-induced …

[HTML][HTML] Curcumin derived from medicinal homologous foods: its main signals in immunoregulation of oxidative stress, inflammation, and apoptosis

P Hu, K Li, XX Peng, Y Kan, TJ Yao, ZY Wang… - Frontiers in …, 2023 - frontiersin.org
It has been for thousands of years in China known medicinal homologous foods that can be
employed both as foods and medicines to benefit human and animal health. These edible …

Identification of two novel prenylated flavonoids in mulberry leaf and their bioactivities

L Wen, D Shi, T Zhou, J Tu, M He, Y Jiang, B Yang - Food chemistry, 2020 - Elsevier
Mulberry leaf is a vegetable used in daily diet. It can bring delicious taste and multiple health
benefits. However, the chemicals responsible for these health benefits remain unveiled. In …

Effects of curcumin on neurological diseases: focus on astrocytes

S Eghbaliferiz, F Farhadi, GE Barreto, M Majeed… - Pharmacological …, 2020 - Springer
Astrocytes are the most abundant glial cells in the central nervous system, and are important
players in both brain injury and neurodegenerative disease. Curcumin (1, 7-bis [4-hydroxy-3 …

Potential roles and molecular mechanisms of bioactive ingredients in Curcumae Rhizoma against breast cancer

P Zhao, J Qiu, C Pan, Y Tang, M Chen, H Song, J Yang… - Phytomedicine, 2023 - Elsevier
Background Breast cancer is the most prevalent cancer worldwide, with high morbidity and
mortality. Despite great advances in the therapeutic strategies, the survival rate in the past …