Transcriptomics in the RNA-seq era

PA McGettigan - Current opinion in chemical biology, 2013 - Elsevier
The transcriptomics field has developed rapidly with the advent of next-generation
sequencing technologies. RNA-seq has now displaced microarrays as the preferred method …

Urinary biomarkers and their potential for the non-invasive detection of endometrial cancer

K Njoku, D Chiasserini, ER Jones, CE Barr… - Frontiers in …, 2020 - frontiersin.org
Endometrial cancer is the most common malignancy of the female genital tract and its
incidence is rising in parallel with the mounting prevalence of obesity. Early diagnosis has …

miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor

NE Renthal, CC Chen, KC Williams… - Proceedings of the …, 2010 - National Acad Sciences
Throughout most of pregnancy, uterine quiescence is maintained by increased
progesterone receptor (PR) transcriptional activity, whereas spontaneous labor is …

Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome

CE Joyce, X Zhou, J Xia, C Ryan… - Human molecular …, 2011 - academic.oup.com
Psoriasis is a chronic and complex inflammatory skin disease with lesions displaying
dramatically altered mRNA expression profiles. However, much less is known about the …

[HTML][HTML] The common marmoset genome provides insight into primate biology and evolution

TMG Sequencing, Analysis Consortium - Nature genetics, 2014 - ncbi.nlm.nih.gov
A first analysis of the genome sequence of the common marmoset (Callithrix jacchus),
assembled using traditional Sanger methods and Ensembl annotation, has permitted …

Circulating exosomal miRNA profile during term and preterm birth pregnancies: a longitudinal study

R Menon, C Debnath, A Lai, D Guanzon… - …, 2019 - academic.oup.com
Despite decades of research in the field of human reproduction, the mechanisms
responsible for human parturition still remain elusive. The objective of this study was to …

Functional microRNA involved in endometriosis

SM Hawkins, CJ Creighton, DY Han… - Molecular …, 2011 - academic.oup.com
Endometriosis is a common disease seen by gynecologists. Clinical features involve pelvic
pain and unexplained infertility. Although endometriosis is pathologically characterized by …

The repertoire and features of human platelet microRNAs

H Plé, P Landry, A Benham, C Coarfa, PH Gunaratne… - PloS one, 2012 - journals.plos.org
Playing a central role in the maintenance of hemostasis as well as in thrombotic disorders,
platelets contain a relatively diverse messenger RNA (mRNA) transcriptome as well as …

MicroRNAs miR-30b, miR-30d, and miR-494 regulate human endometrial receptivity

S Altmäe, JA Martinez-Conejero… - Reproductive …, 2013 - journals.sagepub.com
MicroRNAs (miRNAs) act as important epigenetic posttranscriptional regulators of gene
expression. We aimed to gain more understanding of the complex gene expression …

Guidelines for the design, analysis and interpretation of 'omics' data: focus on human endometrium

S Altmäe, FJ Esteban, A Stavreus-Evers… - Human reproduction …, 2014 - academic.oup.com
BACKGROUND 'Omics' high-throughput analyses, including genomics, epigenomics,
transcriptomics, proteomics and metabolomics, are widely applied in human endometrial …