Leishmaniasis, a neglected parasitic disease caused by a unicellular protozoan of the
genus Leishmania, is transmitted through the bite of a female sandfly. The disease remains …

Leishmaniasis is endemic to the tropical and subtropical regions of the world and is
transmitted by the bite of an infected sand fly. The multifaceted interactions between …

Leishmaniasis, a neglected tropical disease, still remains a global concern for the
healthcare sector. The primary causative agents of the disease comprise diverse …

A remarkable characteristic of infectious diseases classified as Neglected Tropical Diseases
(NTDs) is the fact that they are mostly transmitted in tropical and subtropical regions with …

Abstract Micro RNAs (miRNAs, miRs) and relevant networks might exert crucial functions
during differential host cell infection by the different Leishmania species. Thus, a …

Cytokines are key mediators of immune responses to autoantigens, tumor antigens and
foreign antigens including pathogens and transplant antigens. The cytokines are produced …

Asymptomatic Leishmania infantum, when associated with HIV, can become severe and
potentially fatal. In this co-infection, the worst prognosis may be influenced by the host's …

Background Visceral leishmaniasis (VL) is one of the major public health burden, mainly
distributed throughout tropical and subtropical regions of the world. Among the Sub-Saharan …

Following inoculation of Leishmania, a protozoan parasite, into the skin of a mammal, the
epidermal keratinocytes recognize the parasite and influence the local immune response …

Background Hemophagocytic lymphohistiocytosis (HLH) is known as a life-threatening
syndrome, and Leishmania is the most common protozoan that triggers infection-related …