Maternal and paternal factors influence offspring development and program its genome for
successful postnatal life. Based on the stressors during gestation, the pregnant female …

Complications of pregnancy remain key drivers of morbidity and mortality, affecting the
health of both the mother and her offspring in the short and long term. There is lack of …

Zika virus (ZIKV) is an arbovirus belonging to the genus Flavivirus (family Flaviviridae) and
was first described in 1947 in Uganda following blood analyses of sentinel Rhesus …

The placenta responds to adverse environmental conditions by adapting its capacity for
substrate transfer to maintain fetal growth and development. Early-onset hypoxia effects on …

High-altitude hypoxia acclimatization requires whole-body physiological regulation in
highland immigrants, but the underlying genetic mechanism has not been clarified. Here we …

Hypoxia is the failure of oxygenation at the tissue level, where the reduced oxygen delivered
is not enough to satisfy tissue demands. Metabolic depression is the physiological …

Background Hypoxia is associated with pregnancy complications, such as preeclampsia,
placental abruption, and gestational sleep apnea. Hypoxic insults during gestation can …

This pre-eminent work has developed over six editions in response to man's attempts to
climb higher and higher unaided, and to spend more time at altitude for both work and …

Fetal growth restriction (FGR) is defined as the failure of fetus to reach its growth potential for
various reasons, leading to multiple perinatal complications and adult diseases of fetal …

Progress in the study of pregnancy complicated by chronic hypoxia in large mammals has
been held back by the inability to measure long‐term significant reductions in fetal …