[HTML][HTML] Regulation of adipose thermogenesis and its critical role in glucose and lipid metabolism
L Wang, Y Qiu, H Gu, M Gan, Y Zhu, K Zhu… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
The function of the adipose tissue is influenced by complex interactions between genetics,
epigenetics, and the environment, and its dysfunction can cause a variety of metabolic …
epigenetics, and the environment, and its dysfunction can cause a variety of metabolic …
Obesity and obstructive sleep apnea
MR Bonsignore - From Obesity to Diabetes, 2021 - Springer
Obstructive sleep apnea (OSA) is characterized by upper airway collapse during sleep.
Chronic intermittent hypoxia, sleep fragmentation, and inflammatory activation are the main …
Chronic intermittent hypoxia, sleep fragmentation, and inflammatory activation are the main …
[HTML][HTML] Using single-nucleus RNA-sequencing to interrogate transcriptomic profiles of archived human pancreatic islets
Background Human pancreatic islets are a central focus of research in metabolic studies.
Transcriptomics is frequently used to interrogate alterations in cultured human islet cells …
Transcriptomics is frequently used to interrogate alterations in cultured human islet cells …
[HTML][HTML] Chronic intermittent hypoxia impaired collagen synthesis in mouse genioglossus via ROS accumulation: A transcriptomic analysis
MH Zhang, XX Han, Y Lu, JJ Deng, WH Zhang… - Respiratory Physiology …, 2023 - Elsevier
Obstructive sleep apnea (OSA) is a sleep-related breathing disorder characterized by
intermittent and recurrent upper airway collapse during sleep that leads to chronic …
intermittent and recurrent upper airway collapse during sleep that leads to chronic …
Senolytic-facilitated reversal of end-organ dysfunction in a murine model of obstructive sleep apnea
Rationale: Obstructive sleep apnea (OSA) is a highly prevalent condition that is associated
with accelerated biological aging and multiple end-organ morbidities. Current treatments …
with accelerated biological aging and multiple end-organ morbidities. Current treatments …
Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial
A Briançon‐Marjollet, M Netchitaïlo… - Journal of Sleep …, 2024 - Wiley Online Library
Sympathetic overactivity caused by chronic intermittent hypoxia is a hallmark of obstructive
sleep apnea. A high sympathetic tone elicits increases in plasma free fatty acid and insulin …
sleep apnea. A high sympathetic tone elicits increases in plasma free fatty acid and insulin …
[HTML][HTML] Genetic and Lifestyle-Related Factors Influencing Serum Hyper-Propionylcarnitine Concentrations and Their Association with Metabolic Syndrome and …
YH Lee, S Park - International Journal of Molecular Sciences, 2023 - mdpi.com
The genetic and environmental determinants of serum propionylcarnitine concentrations
(PC) remain largely unexplored. This study investigated the impact of genetic and …
(PC) remain largely unexplored. This study investigated the impact of genetic and …