Beyond benzodiazepines: a meta-analysis and narrative synthesis of the efficacy and safety of alternative options for alcohol withdrawal syndrome management

D Fluyau, VK Kailasam, CG Pierre - European Journal of Clinical …, 2023 - Springer
Purpose To compare the efficacy and safety of non-benzodiazepines (non-BZDs) to
benzodiazepines (BZDs) in the treatment of alcohol withdrawal syndrome (AWS). Methods …

A narrative review of current and emerging trends in the treatment of alcohol use disorder

M Celik, MS Gold, B Fuehrlein - Brain Sciences, 2024 - mdpi.com
Alcohol use disorder (AUD) is a significant contributor to morbidity and mortality in the
United States. It contributes to over 140,000 annual deaths, to over 200 related diseases …

Systematic review and meta-analysis: Efficacy and safety of baclofen in patients with alcohol use disorder co-morbid liver diseases

F Duan, H Zhai, C Liu, C Chang, S Song, J Li… - Journal of Psychiatric …, 2023 - Elsevier
Baclofen is the only drug that has been investigated in randomized controlled studies for anti-
craving in patients with alcohol use disorder (AUD) and liver disease. However, the results …

Assessing the pharmaceutical residues as hotspots of the main rivers of Catalonia, Spain

P Domínguez-García, L Fernández-Ruano… - … Science and Pollution …, 2024 - Springer
The global increase in pharmaceutical consumption, driven by factors such as aging
populations and chronic diseases, has raised concerns regarding the environmental impact …

Understanding motivations and use typologies of gabapentin with opioid agonist medications

MS Ellis, R Qureshi, ME Buttram - Drug and Alcohol Dependence, 2023 - Elsevier
Background Prior research suggests a potential relationship between the nonmedical use of
gabapentin and use of opioid agonist medications (OAMs), buprenorphine and methadone …

[HTML][HTML] Gabapentin alleviates peripheral nerve sensitization induced by inflammatory arthritis via ionotropic glutamate receptor NR2B subunit

Y Meng, M Tan, XY Jiang, T Wang, HL Shen - Neuroscience, 2024 - Elsevier
Inflammatory arthritis leads to peripheral nerve sensitization, but the therapeutic effect is
often unsatisfactory. Our preliminary studies have found that in mice with inflammatory …

Hepatoprotective potentials of Usnea longissima Ach. and Xanthoparmelia somloensis (Gyelnik) Hale extracts in ethanol-induced liver injury

M Berköz, A Aslan, O Yunusoğlu… - Drug and Chemical …, 2024 - Taylor & Francis
In our study, the antioxidant and anti-inflammatory effects of different lichen applications
were investigated in rats using an experimental ethanol toxicity model. 48 rats were used in …

[HTML][HTML] Management of alcohol withdrawal syndrome in patients with alcohol-associated liver disease

JA Ratner, H Blaney, DA Rastegar - Hepatology Communications, 2024 - journals.lww.com
Alcohol-associated liver disease is a common and severe sequela of excessive alcohol use;
effective treatment requires attention to both liver disease and underlying alcohol use …

Managing Alcohol Withdrawal Syndrome

M Gottlieb, N Chien, B Long - Annals of Emergency Medicine, 2024 - Elsevier
Alcohol is a commonly used psychoactive agent, with up to 40% of people reporting heavy
alcohol use or alcohol use disorder during their lifetime. 1, 2, 3 Alcohol use disorder is …

Repurposing drugs for treatment of alcohol use disorder.

HJ Aubin - International Review of Neurobiology, 2024 - europepmc.org
Repurposing drugs for the treatment of alcohol dependence involves the use of drugs that
were initially developed for other conditions, but have shown promise in reducing alcohol …