Abstract Purpose of the Review Apolipoprotein (APO) A1, the main apolipoprotein of plasma
high-density lipoproteins (HDLs), has several well documented cardioprotective functions. A …

Apolipoprotein AI (ApoA-I), the major protein component of high-density lipoproteins (HDL)
is a multifunctional protein, involved in cholesterol traffic and inflammatory and immune …

Abstract The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of
Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic …

Observational studies have reported inconsistent associations between circulating lipids
and breast cancer risk. Using results from> 400,000 participants in two-sample Mendelian …

Background Cancer is emerging as a major problem globally, as it accounts for the second
cause of death despite medical advances. According to epidemiological and basic studies …

The epidemiological evidence for an obesity‐cancer association is solid, whereas the
association between obesity‐associated lipoprotein levels and cancer is less evident. We …

Breast cancer is the most prevalent cancer and primary cause of cancer-related mortality in
women. The identification of risk factors can improve prevention of cancer, and obesity and …

Metabolic syndrome is a type of multifactorial metabolic disease with the presence of at least
three factors: obesity, diabetes mellitus, low high-density lipoprotein, hypertriglyceridemia …

The objective of the present study was to conduct the first systematic review and meta-
analysis of prospective studies investigating the associations between total cholesterol (TC) …

Background: Lipid biomarkers, such as HDL-cholesterol concentrations, have been shown
to have positive, inverse, and null associations with total, breast, and colorectal cancer risks …