Research progress on the anti-aging potential of the active components of ginseng

J Su, Q Su, S Hu, X Ruan, S Ouyang - Nutrients, 2023 - mdpi.com
Aging is a cellular state characterized by a permanent cessation of cell division and evasion
of apoptosis. DNA damage, metabolic dysfunction, telomere damage, and mitochondrial …

The anti-aging mechanism of ginsenosides with medicine and food homology

T Tian, CN Ko, W Luo, D Li, C Yang - Food & Function, 2023 - pubs.rsc.org
With the acceleration of global aging and the rise in living standards, the achievement of
healthy aging is becoming an imperative issue globally. Ginseng, a medicinal plant that has …

Anti-aging activity and modes of action of compounds from natural food sources

L Song, S Zhang - Biomolecules, 2023 - mdpi.com
Aging is a natural and inescapable phenomenon characterized by a progressive
deterioration of physiological functions, leading to increased vulnerability to chronic …

Ginsenoside Re blocks Bay k-8644-induced neurotoxicity via attenuating mitochondrial dysfunction and PKCδ activation in the hippocampus of mice: Involvement of …

NKC Tran, JH Jeong, N Sharma, YND Nguyen… - Food and Chemical …, 2023 - Elsevier
Although the anticonvulsant effects of ginsenosides are recognized, little is known about
their effects on the convulsive behaviors induced by the activation of L-type Ca 2+ channels …

Demethylzeylasteral protects against renal interstitial fibrosis by attenuating mitochondrial complex I-mediated oxidative stress

P Shen, X Deng, T Li, X Chen, X Wu - Journal of Ethnopharmacology, 2024 - Elsevier
Ethnopharmacological relevance Renal interstitial fibrosis (RIF) is a main pathological
process in chronic kidney disease (CKD). Demethylzeylasteral (DML), a major component of …

Ginsenoside Re mitigates memory impairments in aged GPx-1 KO mice by inhibiting the interplay between PAFR, NFκB, and microgliosis in the hippocampus

EJ Shin, BT Nguyen, N Sharma, NKC Tran… - Food and Chemical …, 2023 - Elsevier
Abstract Ginsenoside Re (GRe) upregulates anti-aging klotho by mainly upregulating
glutathione peroxidase-1 (GPx-1). However, the anti-aging mechanism of GPx-1 remains …

Research on the anti-aging mechanisms of Panax ginseng extract in mice: a gut microbiome and metabolomics approach

L Lin, R Tang, Y Liu, Z Li, H Li, H Yang - Frontiers in Pharmacology, 2024 - frontiersin.org
Introduction: Aged-related brain damage and gut microbiome disruption are common.
Research affirms that modulating the microbiota-gut-brain axis can help reduce age-related …

Efficacy and Safety of Panax ginseng Sprout Extract in Subjective Memory Impairment: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

HI Baek, KC Ha, YK Park, TY Kim, SJ Park - Nutrients, 2024 - mdpi.com
Sprout ginseng extract (ThinkGIN™) manufactured through a smart farm system has been
shown to improve memory in preclinical studies. This study conducted a 12-week …

Therapeutic potential and possible mechanisms of ginseng for depression associated with COVID-19

F Zhao, K Zhang, H Chen, T Zhang, J Zhao, Q Lv… - …, 2024 - Springer
Recently, a global outbreak of COVID-19 has rapidly spread to various national regions. As
the number of COVID-19 patients has increased, some of those infected with SARS-CoV-2 …

Study on the anti-skin aging effect and mechanism of Sijunzi Tang based on network pharmacology and experimental validation

H Ke, X Zhang, S Liang, C Zhou, Y Hu, Q Huang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Si Jun Zi Tang (SJZT) is a famous traditional
Chinese medicine formula composing of 4 herbal medicines (Ginseng Radix et Rhizoma …