The role of myofibroblasts in physiological and pathological tissue repair

R Schuster, F Younesi, M Ezzo… - Cold Spring Harbor …, 2023 - cshperspectives.cshlp.org
Myofibroblasts are the construction workers of wound healing and repair damaged tissues
by producing and organizing collagen/extracellular matrix (ECM) into scar tissue. Scar tissue …

Bioprinting: From Tissue and Organ Development to in Vitro Models

C Mota, S Camarero-Espinosa, MB Baker… - Chemical …, 2020 - ACS Publications
Bioprinting techniques have been flourishing in the field of biofabrication with pronounced
and exponential developments in the past years. Novel biomaterial inks used for the …

The role of myofibroblasts in wound healing

B Hinz - Current research in translational medicine, 2016 - Elsevier
The importance of proper skin wound healing becomes evident when our body's repair
mechanisms fail, leading to either non-healing (chronic) wounds or excessive repair …

The role of hypoxia-inducible factor in wound healing

WX Hong, MS Hu, M Esquivel, GY Liang… - Advances in wound …, 2014 - liebertpub.com
Significance: Poor wound healing remains a significant health issue for a large number of
patients in the United States. The physiologic response to local wound hypoxia plays a …

Mechanoregulation of the myofibroblast in wound contraction, scarring, and fibrosis: opportunities for new therapeutic intervention

L Van De Water, S Varney, JJ Tomasek - Advances in wound care, 2013 - liebertpub.com
Significance: Myofibroblasts are responsible for wound closure that occurs in healed acute
wounds. However, their actions can result in disfiguring scar contractures, compromised …

Modelling skin wound healing angiogenesis: A review

A Guerra, J Belinha, RN Jorge - Journal of theoretical biology, 2018 - Elsevier
The occurrence of wounds is a main health concern in Western society due to their high
frequency and treatment cost. During wound healing, the formation of a functional blood …

Hypoxia and hypoxia signaling in tissue repair and fibrosis

Z Lokmic, J Musyoka, TD Hewitson, IA Darby - International review of cell …, 2012 - Elsevier
Following injury, vascular damage results in the loss of perfusion and consequent low
oxygen tension (hypoxia) which may be exacerbated by a rapid influx of inflammatory and …

Lignin-mediated green synthesis of AgNPs in carrageenan matrix for wound dressing applications

L Jaiswal, S Shankar, JW Rhim, DH Hahm - International journal of …, 2020 - Elsevier
Carrageenan-based functional wound dressing materials were prepared through a one-pot
green synthesis of silver nanoparticles (AgNPs) using lignin as a reducing and capping …

Reactive oxygen species and NOX enzymes are emerging as key players in cutaneous wound repair

D André-Lévigne, A Modarressi, MS Pepper… - International journal of …, 2017 - mdpi.com
Our understanding of the role of oxygen in cell physiology has evolved from its long-
recognized importance as an essential factor in oxidative metabolism to its recognition as an …

[HTML][HTML] Improving hard metal implant and soft tissue integration by modulating the “inflammatory-fibrous complex” response

P Huang, J Xu, L Xie, G Gao, S Chen, Z Gong, X Lao… - Bioactive Materials, 2023 - Elsevier
Soft tissue integration is one major difficulty in the wide applications of metal materials in soft
tissue-related areas. The inevitable inflammatory response and subsequent fibrous reaction …