The lymphatic system, composed of initial and collecting lymphatic vessels as well as lymph
nodes that are present in almost every tissue of the human body, acts as an essential …

The lymphatic system is comprised of a network of vessels interrelated with lymphoid tissue,
which has the holistic function to maintain the local physiologic environment for every cell in …

Immune privilege of the central nervous system (CNS) has been ascribed to the presence of
a blood–brain barrier and the lack of lymphatic vessels within the CNS parenchyma …

Lymphatic vessels collect interstitial fluid that has extravasated from blood vessels and
return it to the circulatory system. Another important function of the lymphatic network is to …

RhoA is a ubiquitously expressed cytoplasmic protein that belongs to the family of small
GTPases. RhoA acts as a molecular switch that is activated in response to binding of …

Trafficking of tissue dendritic cells (DCs) via lymph is critical for the generation of cellular
immune responses in draining lymph nodes (LNs). In the current study we found that DCs …

Lymphatic vessels are well known to participate in the immune response by providing the
structural and functional support for the delivery of antigens and antigen presenting cells to …

T cell migration within and between peripheral tissues and secondary lymphoid organs is
essential for proper functioning of adaptive immunity. While active T cell migration within a …

CCR7, collaborated with its ligands CCL19 and CCL21, controls extensive migratory events
in the immune system. CCR7-bearing dendritic cells can swarm into T-cell zones in lymph …

The lymphatics fulfill a vital physiological function as the conduits through which leucocytes
traffic between the tissues and draining lymph nodes for the initiation and modulation of …