There are well-established disparities in cancer incidence and outcomes by race/ethnicity
that result from the interplay between structural, socioeconomic, socio-environmental …

Black men are disproportionately affected by prostate cancer (PCa), with earlier
presentation, more aggressive disease, and higher mortality rates versus White men …

The past few years have witnessed a revolution in our ability to obtain DNA from ancient
humans. This important new data has added to our knowledge from archaeology and …

Genome-wide association studies (GWAS) provide an agnostic approach for investigating
the genetic basis of complex diseases. In oncology, GWAS of nearly all common …

MYC regulates a complex biological program by transcriptionally activating and repressing
its numerous target genes. As such, MYC is a master regulator of many processes, including …

CONTEXT: Wide variation exists internationally for prostate cancer (PCa) rates due to
differences in detection practices, treatment, and lifestyle and genetic factors. OBJECTIVE …

Prostate cancer rates vary substantially by race, ethnicity, and geography. These disparities
can be explained by variation in access to screening and treatment, variation in exposure to …

Although genome-wide association studies have successfully identified thousands of risk
loci for complex traits, only a handful of the biologically causal variants, responsible for …

Genome-wide association studies have identified hundreds of genetic variants associated
with complex human diseases and traits, and have provided valuable insights into their …

There is a growing attention toward personalized medicine. This is led by a fundamental
shift from the 'one size fits all'paradigm for treatment of patients with conditions or …