[HTML][HTML] Jet injectors: Perspectives for small volume delivery with lasers

J Schoppink, DF Rivas - Advanced drug delivery reviews, 2022 - Elsevier
Needle-free jet injectors have been proposed as an alternative to injections with hypodermic
needles. Currently, a handful of commercial needle-free jet injectors already exist. However …

Vaccination into the dermal compartment: techniques, challenges, and prospects

J Hettinga, R Carlisle - Vaccines, 2020 - mdpi.com
In 2019, an 'influenza pandemic'and 'vaccine hesitancy'were listed as two of the top 10
challenges to global health by the WHO. The skin is a unique vaccination site, due to its …

Trial watch: oncolytic viruses for cancer therapy

J Pol, N Bloy, F Obrist, A Eggermont, J Galon… - …, 2014 - Taylor & Francis
Oncolytic viruses are natural or genetically modified viral species that selectively infect and
kill neoplastic cells. Such an innate or exogenously conferred specificity has generated …

Delivery systems for intradermal vaccination

YC Kim, C Jarrahian, D Zehrung, S Mitragotri… - Intradermal …, 2012 - Springer
Intradermal (ID) vaccination can offer improved immunity and simpler logistics of delivery,
but its use in medicine is limited by the need for simple, reliable methods of ID delivery. ID …

Recent insights into cutaneous immunization: How to vaccinate via the skin

L Engelke, G Winter, S Hook, J Engert - Vaccine, 2015 - Elsevier
Technologies and strategies for cutaneous vaccination have been evolving significantly
during the past decades. Today, there is evidence for increased efficacy of cutaneously …

Biosafety of DNA vaccines: New generation of DNA vectors and current knowledge on the fate of plasmids after injection

F Faurez, D Dory, V Le Moigne, R Gravier, A Jestin - Vaccine, 2010 - Elsevier
DNA vaccination has been widely studied to develop new, alternative, efficient and safe
vaccines for humans and animals. Many efforts have been made to increase the immunising …

Intradermal vaccination using the novel microneedle device MicronJet600: Past, present, and future

Y Levin, E Kochba, I Hung, R Kenney - Human vaccines & …, 2015 - Taylor & Francis
Intradermal immunization has become a forefront of vaccine improvement, both scientifically
and commercially. Newer technologies are being developed to address the need to reduce …

DNA-based vaccination against hepatitis B virus using dissolving microneedle arrays adjuvanted by cationic liposomes and CpG ODN

Y Qiu, L Guo, S Zhang, B Xu, Y Gao, Y Hu, J Hou… - Drug …, 2016 - Taylor & Francis
DNA vaccines are simple to produce and can generate strong cellular and humoral immune
response, making them attractive vaccine candidates. However, a major shortcoming of …

Therapeutic hpv DNA vaccines

K Lin, E Roosinovich, B Ma, CF Hung, TC Wu - Immunologic research, 2010 - Springer
It is now well established that most cervical cancers are causally associated with HPV
infection. This realization has led to efforts to control HPV-associated malignancy through …

DNA vaccines to attack cancer: Strategies for improving immunogenicity and efficacy

A Tiptiri-Kourpeti, K Spyridopoulou, A Pappa… - Pharmacology & …, 2016 - Elsevier
DNA vaccination represents a smart and promising approach to cancer immunotherapy.
DNA vaccines for cancer immunotherapy are designed to deliver one or several genes …