The first effective Brucella vaccine was based on live Brucella abortus strain 19, a laboratory-
derived strain attenuated by an unknown process during subculture. This induces …

Brucella abortus vaccines play a central role in bovine brucellosis control/eradication
programs and have been successfully used worldwide for decades. Strain 19 and RB51 are …

-Brucellosis control and eradication requires serological tests and vaccines. Effective
classical vaccines (S19 in cattle and Rev 1 in small ruminants), however, induce antibodies …

Brucella abortus is a facultative intracellular gram-negative bacterial pathogen that infects
humans and animals by entry mainly through the digestive tract. B. abortus causes abortion …

The P39 and the bacterioferrin (BFR) antigens of Brucella melitensis 16M were previously
identified as T dominant antigens able to induce both delayed-type hypersensivity in …

Brucella abortus is the etiologic agent of bovine brucellosis and causes a chronic disease in
humans known as undulant fever. In livestock the disease is characterized by abortion and …

Brucella abortus live vaccines have been used successfully to control bovine brucellosis
worldwide for decades. However, due to some limitations of these live vaccines, efforts are …

Brucellosis is a livestock disease responsible for fetal loss due to abortions. Worldwide, this
disease has profound economic and social impact by reducing the ability of livestock …

Brucellosis is one of the most prevalent bacterial zoonosis of worldwide distribution. The
disease is caused by Brucella spp., facultative intracellular pathogens. Brucellosis in …

This study was conducted to evaluate the immunogenicity and protective efficacy of a DNA
vaccine encoding Brucella abortus Cu, Zn superoxide dismutase (SOD). Intramuscular …