Tutorial: multivariate classification for vibrational spectroscopy in biological samples

CLM Morais, KMG Lima, M Singh, FL Martin - Nature Protocols, 2020 - nature.com
Vibrational spectroscopy techniques, such as Fourier-transform infrared (FTIR) and Raman
spectroscopy, have been successful methods for studying the interaction of light with …

Fourier transform infrared spectroscopy in oral cancer diagnosis

R Wang, Y Wang - International journal of molecular sciences, 2021 - mdpi.com
Oral cancer is one of the most common cancers worldwide. Despite easy access to the oral
cavity and significant advances in treatment, the morbidity and mortality rates for oral cancer …

Is infrared spectroscopy ready for the clinic?

D Finlayson, C Rinaldi, MJ Baker - Analytical chemistry, 2019 - ACS Publications
Fourier transform-infrared spectroscopy (FT-IR) represents an attractive molecular
diagnostic modality for translation to the clinic, where comprehensive chemical profiling of …

Spectral pre and post processing for infrared and Raman spectroscopy of biological tissues and cells

HJ Byrne, P Knief, ME Keating, F Bonnier - Chemical Society Reviews, 2016 - pubs.rsc.org
Vibrational spectroscopy, both infrared absorption and Raman spectroscopy, have attracted
increasing attention for biomedical applications, from in vivo and ex vivo disease diagnostics …

Clinical applications of infrared and Raman spectroscopy: state of play and future challenges

MJ Baker, HJ Byrne, J Chalmers, P Gardner… - Analyst, 2018 - pubs.rsc.org
Vibrational spectroscopies, based on infrared absorption and/or Raman scattering provide a
detailed fingerprint of a material, based on the chemical content. Diagnostic and prognostic …

Multimodal imaging based on vibrational spectroscopies and mass spectrometry imaging applied to biological tissue: a multiscale and multiomics review

M Tuck, L Blanc, R Touti, NH Patterson… - Analytical …, 2020 - ACS Publications
Molecular imaging has the potential to unearth important spatial and temporal relationships
in biological systems, including intercellular signaling as well as environmentally-cued …

Fundamental developments in infrared spectroscopic imaging for biomedical applications

M Pilling, P Gardner - Chemical Society reviews, 2016 - pubs.rsc.org
Infrared chemical imaging is a rapidly emerging field with new advances in instrumentation,
data acquisition and data analysis. These developments have had significant impact in …

Infrared spectroscopic imaging advances as an analytical technology for biomedical sciences

TP Wrobel, R Bhargava - Analytical chemistry, 2018 - ACS Publications
Optical chemical imaging seeks to nondestructively acquire spatially resolved chemical
information without the use of labels or probes. The combination of vibrational mid-infrared …

Large scale infrared imaging of tissue micro arrays (TMAs) using a tunable Quantum Cascade Laser (QCL) based microscope

P Bassan, MJ Weida, J Rowlette, P Gardner - Analyst, 2014 - pubs.rsc.org
Chemical imaging in the field of vibrational spectroscopy is developing into a promising tool
to complement digital histopathology. Applications include screening of biopsy tissue via …

Spectropathology for the next generation: Quo vadis?

HJ Byrne, M Baranska, GJ Puppels, N Stone, B Wood… - Analyst, 2015 - pubs.rsc.org
Although the potential of vibrational spectroscopy for biomedical applications has been well
demonstrated, translation into clinical practice has been relatively slow. This Editorial …