A reactive oxygen species burst causes haploid induction in maize

C Jiang, J Sun, R Li, S Yan, W Chen, L Guo, G Qin… - Molecular Plant, 2022 - cell.com
Haploid induction (HI) is an important tool in crop breeding. Phospholipase A1
(ZmPLA1)/NOT LIKE DAD (NLD)/MATRILINEAL (MTL) is a key gene controlling HI in maize; …

Looking beyond structure: membrane phospholipids of skeletal muscle mitochondria

TD Heden, PD Neufer, K Funai - Trends in Endocrinology & Metabolism, 2016 - cell.com
Skeletal muscle mitochondria are highly dynamic and are capable of tremendous expansion
to meet cellular energetic demands. Such proliferation in mitochondrial mass requires a …

[HTML][HTML] 17β-Estradiol directly lowers mitochondrial membrane microviscosity and improves bioenergetic function in skeletal muscle

MJ Torres, KA Kew, TE Ryan, ER Pennington, CT Lin… - Cell metabolism, 2018 - cell.com
Menopause results in a progressive decline in 17β-estradiol (E2) levels, increased
adiposity, decreased insulin sensitivity, and a higher risk for type 2 diabetes. Estrogen …

The Slo (w) path to identifying the mitochondrial channels responsible for ischemic protection

CO Smith, K Nehrke, PS Brookes - Biochemical Journal, 2017 - portlandpress.com
Mitochondria play an important role in tissue ischemia and reperfusion (IR) injury, with
energetic failure and the opening of the mitochondrial permeability transition pore being the …

Molecular mechanism of cardiolipin-mediated assembly of respiratory chain supercomplexes

C Arnarez, SJ Marrink, X Periole - Chemical Science, 2016 - pubs.rsc.org
Mitochondria produce most of the ATP consumed by cells through the respiratory chain in
their inner membrane. This process involves protein complexes assembled into larger …

Divergent skeletal muscle metabolomic signatures of different exercise training modes independently predict cardiometabolic risk factors

MW Pataky, AP Kumar, DA Gaul, SG Moore… - Diabetes, 2024 - Am Diabetes Assoc
We investigated the link between enhancement of SI (by hyperinsulinemic–euglycemic
clamp) and muscle metabolites after 12 weeks of aerobic (high-intensity interval training …

Docosahexaenoic acid lowers cardiac mitochondrial enzyme activity by replacing linoleic acid in the phospholipidome

EM Sullivan, ER Pennington, GC Sparagna… - Journal of Biological …, 2018 - ASBMB
Cardiac mitochondrial phospholipid acyl chains regulate respiratory enzymatic activity. In
several diseases, the rodent cardiac phospholipidome is extensively rearranged; however …

[HTML][HTML] PFKFB3-mediated glycolysis rescues myopathic outcomes in the ischemic limb

TE Ryan, CA Schmidt, MD Tarpey, AJ Amorese… - Jci Insight, 2020 - ncbi.nlm.nih.gov
Compromised muscle mitochondrial metabolism is a hallmark of peripheral arterial disease,
especially in patients with the most severe clinical manifestation—critical limb ischemia …

Older adults with sarcopenia have distinct skeletal muscle phosphodiester, phosphocreatine, and phospholipid profiles

JM Hinkley, HH Cornnell, RA Standley, EY Chen… - Aging …, 2020 - Wiley Online Library
The loss of skeletal muscle mass and function with age (sarcopenia) is a critical healthcare
challenge for older adults. 31‐phosphorus magnetic resonance spectroscopy (31P‐MRS) is …

[HTML][HTML] The mitochondrial-targeted antioxidant, MitoQ, increases liver mitochondrial cardiolipin content in obesogenic diet-fed rats

G Fouret, E Tolika, J Lecomte, B Bonafos… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Cardiolipin (CL), a unique mitochondrial phospholipid, plays a key role in several processes
of mitochondrial bioenergetics as well as in mitochondrial membrane stability and dynamics …