Cancer researchers have traditionally used the mouse and the rat as staple model
organisms. These animals are very short-lived, reproduce rapidly and are highly prone to …

The discovery of genetic variation and the assembly of genome sequences are both
inextricably linked to advances in DNA-sequencing technology. Short-read massively …

Lifespan varies within and across species, but the general principles of its control remain
unclear. Here, we conducted multi-tissue RNA-seq analyses across 41 mammalian species …

In cases of severe wildlife population decline, a key question is whether recovery efforts will
be impeded by genetic factors, such as inbreeding depression. Decades of excess mortality …

RNA editing by adenosine deaminases changes the information encoded in the mRNA from
its genomic blueprint. Editing of protein-coding sequences can introduce novel, functionally …

Launched in 2001 to showcase the draft human genome assembly, the UCSC Genome
Browser database (http://genome. ucsc. edu) and associated tools continue to grow …

The mammalian radiation has corresponded with rapid changes in noncoding regions of the
genome, but we lack a comprehensive understanding of regulatory evolution in mammals …

The evolution of cetaceans, from their early transition to an aquatic lifestyle to their
subsequent diversification, has been the subject of numerous studies. However, although …

The ancestors of marine mammals once roamed the land and independently committed to
an aquatic lifestyle. These macroevolutionary transitions have intrigued scientists for …

Marine mammals from different mammalian orders share several phenotypic traits adapted
to the aquatic environment and therefore represent a classic example of convergent …