Despite advances in machine learning-based protein structure prediction, we are still far
from fully understanding how proteins fold into their native conformation. The conventional …

Alzheimer's disease (AD) is the most frequent cause of dementia. After decades of research,
we know the importance of the accumulation of protein aggregates such as β-amyloid …

Huntington's disease is a neurodegenerative disease caused by an expanded polyQ stretch
within Huntingtin (HTT) that renders the protein aggregation-prone, ultimately resulting in the …

Autoimmunity plays a key role in the pathogenesis of Alzheimer's disease (AD). However,
whether autoantibodies in peripheral blood can be used as biomarkers for AD has been …

Parkinson's disease (PD) is a neurodegenerative disease characterized by the
degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and …

Amyloid formation is a misfolding process that has been linked to age‐related diseases,
including Alzheimer's and Huntington's. Understanding how cellular factors affect this …

The SERF family of proteins were originally discovered for their ability to accelerate amyloid
formation. Znf706 is an uncharacterized protein whose N-terminus is homologous to SERF …

In age-related neurodegenerative diseases, like Alzheimer's and Parkinson's, disease-
specific proteins become aggregation-prone and form amyloid-like deposits. Depletion of …

Alzheimer's disease (AD) is a devastating, progressive neurodegenerative disease affecting
the elderly in the world. The pathological hallmark senile plaques are mainly composed of …

Peptides with suitable aggregation behavior and electrical properties are potential siRNA
delivery vectors. However, identifying suitable peptides with ideal delivery and safety …