Studying the complex molecular mechanisms involved in traumatic brain injury (TBI) is
crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused …

Traumatic brain injury (TBI) contributes a major cause of death, disability, and mental health
disorders. Most TBI patients suffer long-term post-traumatic stress disorder, cognitive …

2001), 2nd (Prague 2004), and 3rd (Zurich 2008) International Consensus Conference on
Concussion in Sport and is based on the deliberations at the 4th International Conference …

Within minutes of a traumatic impact, a robust inflammatory response is elicited in the injured
brain. The complexity of this post-traumatic squeal involves a cellular component …

Panel discussion regarding the definition of concussion and its separation from mild
traumatic brain injury (mTBI) was held. Although there was acknowledgement that the terms …

If cytokines are constitutively expressed by and act on neurons in normal adult brain, then
we may have to modify our current view that they are predominantly inflammatory mediators …

Publisher Summary This chapter highlights the controversies concerning the role of brain
inflammation elicited after brain trauma. In clinical practice, classification of primary brain …

A growing body of data suggests that hyperactivation of the immune system has been
implicated in the pathophysiology of major depressive disorder (MDD). Several pro …

Mild traumatic brain injuries (mTBI) have been associated with long-term cognitive deficits
relating to trauma-induced neurodegeneration. These long-term deficits include impaired …

Brain injury (ischemia, trauma) is among the leading cause of mortality and disability in the
western world. It induces increased production of tumor necrosis factor (TNFα) by brain …