IL-10 family cytokines IL-10 and IL-22: from basic science to clinical translation
W Ouyang, A O'Garra - Immunity, 2019 - cell.com
Cytokines are among the most important effector and messenger molecules in the immune
system. They profoundly participate in immune responses during infection and inflammation …
system. They profoundly participate in immune responses during infection and inflammation …
Role of Th22 cells in the pathogenesis of autoimmune diseases
Upon antigenic stimulation, naïve CD4+ T cells differentiate into different subsets and
secrete various cytokines to exert biological effects. Th22 cells, a newly identified CD4+ T …
secrete various cytokines to exert biological effects. Th22 cells, a newly identified CD4+ T …
IL-10 and IL-22 in mucosal immunity: driving protection and pathology
HX Wei, B Wang, B Li - Frontiers in Immunology, 2020 - frontiersin.org
The barrier surfaces of the gastrointestinal tract are in constant contact with various
microorganisms. Cytokines orchestrate the mucosal adaptive and innate immune cells in the …
microorganisms. Cytokines orchestrate the mucosal adaptive and innate immune cells in the …
Interleukin-22: immunobiology and pathology
JA Dudakov, AM Hanash… - Annual review of …, 2015 - annualreviews.org
Interleukin-22 (IL-22) is a recently described IL-10 family cytokine that is produced by T
helper (Th) 17 cells, γδ T cells, NKT cells, and newly described innate lymphoid cells (ILCs) …
helper (Th) 17 cells, γδ T cells, NKT cells, and newly described innate lymphoid cells (ILCs) …
Nutritional applications of species of Spirulina and Chlorella in farmed fish: A review
Microalgae contain 50% crude protein value, which is comparable with the amino acid
profile of fish meal, and high levels of polyunsaturated fatty acids make their use in animal …
profile of fish meal, and high levels of polyunsaturated fatty acids make their use in animal …
Therapeutic opportunities of the IL-22–IL-22R1 system
R Sabat, W Ouyang, K Wolk - Nature reviews Drug discovery, 2014 - nature.com
Abstract Interleukin-22 (IL-22) is a key effector molecule that is produced by activated T cells,
including T helper 22 (TH22) cells, TH17 cells and TH1 cells, as well as subsets of innate …
including T helper 22 (TH22) cells, TH17 cells and TH1 cells, as well as subsets of innate …
Regulation and functions of the IL-10 family of cytokines in inflammation and disease
The IL-10 family of cytokines consists of nine members: IL-10, IL-19, IL-20, IL-22, IL-24, IL-
26, and the more distantly related IL-28A, IL-28B, and IL-29. Evolutionarily, IL-10 family …
26, and the more distantly related IL-28A, IL-28B, and IL-29. Evolutionarily, IL-10 family …
CARD9+ microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment
RA Drummond, M Swamydas, V Oikonomou… - Nature …, 2019 - nature.com
The C-type lectin receptor–Syk (spleen tyrosine kinase) adaptor CARD9 facilitates protective
antifungal immunity within the central nervous system (CNS), as human deficiency in …
antifungal immunity within the central nervous system (CNS), as human deficiency in …
Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases
M Akdis, S Burgler, R Crameri, T Eiwegger… - Journal of allergy and …, 2011 - Elsevier
Advancing our understanding of mechanisms of immune regulation in allergy, asthma,
autoimmune diseases, tumor development, organ transplantation, and chronic infections …
autoimmune diseases, tumor development, organ transplantation, and chronic infections …
Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22
GF Sonnenberg, LA Fouser, D Artis - Nature immunology, 2011 - nature.com
The maintenance of barrier function at exposed surfaces of the mammalian body is essential
for limiting exposure to environmental stimuli, preventing systemic dissemination of …
for limiting exposure to environmental stimuli, preventing systemic dissemination of …