The Kabachnik–Fields reaction: Mechanism and synthetic use

G Keglevich, E Bálint - Molecules, 2012 - mdpi.com
The Kabachnik–Fields (phospha-Mannich) reaction involving the condensation of primary or
secondary amines, oxo compounds (aldehydes and ketones) and> P (O) H species …

Synthesis of α-aminophosphonates and related derivatives; The last decade of the Kabachnik–Fields reaction

PR Varga, G Keglevich - Molecules, 2021 - mdpi.com
The Kabachnik–Fields reaction, comprising the condensation of an amine, oxo compound
and a P-reagent (generally a> P (O) H species or trialkyl phosphite), still attracts interest due …

Visible‐Light‐Driven Selective Oxidative Coupling of Amines to Imines by Bismuth‐Rich Bismuth Oxybromide in Water

W Zhao, C Yang, X Zhang, Y Deng, C Han… - …, 2020 - Wiley Online Library
Photocatalytic selective oxidative coupling of amines is a promising method for imine
synthesis. Bismuth‐rich bismuth oxybromide photocatalysts have been found to exhibit …

New N-acyl-as well as N-phosphonoylmethyl-and N-phosphinoylmethyl-α-amino-benzylphosphonates by acylation and a tandem Kabachnik–Fields protocol

PR Varga, K Karaghiosoff, ÉV Sári, A Simon… - Organic & …, 2023 - pubs.rsc.org
Diethyl α-benzylamino-and α-amino-benzylphosphonates obtained by the Kabachnik–
Fields reaction were useful intermediates in the synthesis of other derivatives. Acylation of α …

N-Benzyl and N-aryl bis (phospha-Mannich adducts): Synthesis and catalytic activity of the related bidentate chelate platinum complexes in hydroformylation

E Bálint, E Fazekas, P Pongrácz, L Kollár… - Journal of …, 2012 - Elsevier
The microwave-assisted double Kabachnik–Fields (phospha-Mannich) reaction of
benzylamine and arylamines, two equivalents of paraformaldehyde and the P (O) H reagent …

Phospha-Mannich reactions of PH3 and its analogs

DV Moiseev, BR James - Phosphorus, Sulfur, and Silicon and the …, 2022 - Taylor & Francis
The easiest route to form compounds with P–C sp3–N linkage (s) is phosphorus-based
Mannich-type reactions (phospha-Mannich reactions) between phosphines (R3P, R2PH …

A neighbouring group effect leading to enhanced nucleophilic substitution of amines at the hindered α-carbon atom of an α-hydroxyphosphonate

NZ Kiss, A Kaszás, L Drahos, Z Mucsi, G Keglevich - Tetrahedron letters, 2012 - Elsevier
Diethyl α-hydroxy-benzylphosphonate undergoes nucleophilic substitution with primary
amines of sufficient reactivity at around 100° C to afford the corresponding α …

Feedback control of oximation reaction by inline Raman spectroscopy

I Csontos, H Pataki, A Farkas, H Bata… - … Process Research & …, 2015 - ACS Publications
Although the process analytical technology for ensuring constant product quality and tight
control over the manufacturing process, which is especially important in the case of …

The Synthesis of N,N‐Bis(dialkoxyphosphinoylmethyl)‐ and N,N‐Bis(diphenylphosphinoylmethyl)glycine Esters by the Microwave‐Assisted Double Kabachnik …

E Balint, E Fazekas, L Drahos… - Heteroatom …, 2013 - Wiley Online Library
The condensation of a glycine ester, two equivalents of paraformaldehyde, and the same
quantity of a dialkyl phosphite or diphenylphosphine oxide afforded the title compounds as …

Asymmetric Electrophilic Reactions in Phosphorus Chemistry

AO Kolodiazhna, OI Kolodiazhnyi - Symmetry, 2020 - mdpi.com
This review is devoted to the theoretic and synthetic aspects of asymmetric electrophilic
substitution reactions at the stereogenic phosphorus center. The stereochemistry and …