Study of Degradation Kinetics and Structural Analysis of Related Substances of Ceftobiprole by HPLC with UV and MS/MS Detection
D Boczar, K Bus, K Michalska - International Journal of Molecular …, 2022 - mdpi.com
Ceftobiprole is a novel β-lactam antibiotic, active against methicillin-resistant
Staphylococcus aureus, vancomycin-resistant S. aureus and penicillin-resistant …
Staphylococcus aureus, vancomycin-resistant S. aureus and penicillin-resistant …
Application of 1,1‐ADEQUATE and DFT to correct 13C misassignments of carbonyl chemical shifts for carbapenem antibiotics
Prior to the development of sensitive proton‐detected 2D NMR experiments, assigning 13C
signals could be a significant challenge, and mistakes have occurred even for prominent …
signals could be a significant challenge, and mistakes have occurred even for prominent …
Using water proton NMR to characterize aluminum-adjuvanted vaccines
KT Briggs, MB Taraban, YB Yu - 2024 - books.rsc.org
Aluminum-adjuvanted vaccines are a major class of prophylactics used to immunize people
against a wide-range of infectious diseases. 1 There are over 30 marketed aluminum …
against a wide-range of infectious diseases. 1 There are over 30 marketed aluminum …
A validated LC-MS/MS method for the simultaneous quantification of the novel combination antibiotic, ceftolozane–tazobactam, in plasma (total and unbound), CSF …
Objectives Novel treatment options for some carbapenem-resistant Gram-negative
pathogens have been identified by the World Health Organization as being of the highest …
pathogens have been identified by the World Health Organization as being of the highest …
Applications of NMR in Drug Substance and Drug Product Development
MVS Elipe - 2024 - books.rsc.org
In the pharmaceutical industry, the development of a drug candidate comes after the drug
has been discovered during the research and discovery process and tested in animals …
has been discovered during the research and discovery process and tested in animals …
Identification and Structure Elucidation of Compounds: Deleting 'Un'from the Unknowns
The occurrence of unknown compounds is a major consideration in many analytical fields.
HRMS forms a basis of unknown identification analysis procedures, in accordance with the …
HRMS forms a basis of unknown identification analysis procedures, in accordance with the …