Alcoholism is associated with brain damage and impaired cognitive functioning. The relative
contributions of different etiological factors, such as alcohol, thiamine deficiency and age …

As the percentage of the global population over age 65 grows, and with it a subpopulation of
individuals with alcohol use disorder (AUD), understanding the effect of alcohol on the aged …

Neuroimmune pathways regulate brain function to influence complex behavior and play a
role in several neuropsychiatric diseases, including alcohol use disorder (AUD). In …

Alcohol binge drinking allows the translocation of bacterial lipopolysaccharide (LPS) from
the gut to the blood, which activates the peripheral immune system with consequences in …

The pathophysiological mechanisms behind amnesia are still unknown. Recent literature,
through the study of patients with Alcohol Use Disorder with and without Korsakoff's …

The passage of time dictates the pace at which humans and other organisms age but falls
short of providing a complete portrait of how environmental, lifestyle and underlying …

The thalamus, a significant part of the diencephalon, is a symmetrical and bilateral central
brain structure. The thalamus is subdivided into three major groups of nuclei based on their …

There is an increasing awareness of the link between chronic alcohol consumption and the
development of cognitive, behavioural and functional deficits. Currently, preventative …

Wernicke's encephalopathy (WE) is a neurologic disease caused by vitamin B1 or thiamine
deficiency (TD), being the alcohol use disorder its main risk factor. WE patients present …

Benfotiamine (S-benzoylthiamine-O-monophosphate), a unique, lipid-soluble derivative of
thiamine, is the most potent allithiamine found in roasted garlic, as well as in other herbs of …