Aging-related disorders and mitochondrial dysfunction: a critical review for prospect mitoprotective strategies based on mitochondrial nutrient mixtures

G Pagano, FV Pallardó, A Lyakhovich, L Tiano… - International Journal of …, 2020 - mdpi.com
A number of aging-related disorders (ARD) have been related to oxidative stress (OS) and
mitochondrial dysfunction (MDF) in a well-established body of literature. Most studies …

The close interplay of nitro-oxidative stress, advanced glycation end products and inflammation in inflammatory bowel diseases

FA Moura, MOF Goulart, SBG Campos… - Current medicinal …, 2020 - ingentaconnect.com
Background: Inflammatory Bowel Disease (IBD) exhibits no defined aetiology. However,
factors such as genetic and nitro-oxidative stress are associated with chronic inflammation …

[HTML][HTML] Oxidative stress resulting from the removal of endogenous catalase induces obesity by promoting hyperplasia and hypertrophy of white adipocytes

SK Shin, HW Cho, SE Song, SS Im, JH Bae, DK Song - Redox biology, 2020 - Elsevier
Obesity is regarded as an abnormal expansion and excessive accumulation of fat mass in
white adipose tissue. The involvement of oxidative stress in the development of obesity is …

Dental pulp stem cells overexpressing hepatocyte growth factor facilitate the repair of DSS-induced ulcerative colitis

N Li, Y Zhang, N Nepal, G Li, N Yang, H Chen… - Stem Cell Research & …, 2021 - Springer
Background Ulcerative colitis (UC) is a chronic and recurrent disease without satisfactory
treatment strategies. Dental pulp stem cell (DPSC) transplantation has been proposed as a …

High-fructose corn syrup promotes proinflammatory Macrophage activation via ROS-mediated NF-κB signaling and exacerbates colitis in mice

L Wang, T Ji, Y Yuan, H Fu, Y Wang, S Tian… - International …, 2022 - Elsevier
The dramatically increasing incidence and prevalence of inflammatory bowel disease (IBD)
are reportedly related to a Western diet, which is characterized by high sugar consumption …

Ablation of catalase promotes non-alcoholic fatty liver via oxidative stress and mitochondrial dysfunction in diet-induced obese mice

SK Shin, HW Cho, SE Song, JH Bae, SS Im… - … -European Journal of …, 2019 - Springer
Abstract Hydrogen peroxide (H 2 O 2) produced endogenously can cause mitochondrial
dysfunction and metabolic complications in various cell types by inducing oxidative stress. In …

[HTML][HTML] Preventing colitis-associated colon cancer with antioxidants: A systematic review

T Irrazabal, BK Thakur, K Croitoru, A Martin - Cellular and Molecular …, 2021 - Elsevier
Inflammatory bowel disease (IBD) patients have an increased risk of developing colitis-
associated colon cancer (CAC); however, the basis for inflammation-induced genetic …

[PDF][PDF] Therapeutic effects of N-acetyl-L-cysteine on liver damage induced by long-term CCl4 administration

O Otrubová, L Turecký, O Uličná, P Janega… - Gen. Physiol …, 2018 - academia.edu
N-acetyl-L-cysteine (NAC) is a drug routinely used in several health problems, eg liver
damage. There is some information emerged on its negative effects in certain situations. The …

Extraintestinal Manifestations in Induced Colitis: Controversial Effects of N‐Acetylcysteine on Colon, Liver, and Kidney

AS da Paz Martins, KQ de Andrade… - Oxidative Medicine …, 2023 - Wiley Online Library
Ulcerative colitis (UC) is a chronic and recurrent inflammatory bowel disease (IBD)
characterized by continuous inflammation in the colonic mucosa. Extraintestinal …

New insights on the modulatory roles of metformin or alpha-lipoic acid versus their combination in dextran sulfate sodium-induced chronic colitis in rats

FS Samman, SM Elaidy, SS Essawy… - Pharmacological Reports, 2018 - Elsevier
Background Dextran sulfate sodium (DSS)-induced colitis is the most widely used model
that resembles ulcerative colitis (UC) in human with challenging chronic mechanistic …