[HTML][HTML] Could SARS-CoV-2 spike protein be responsible for long-COVID syndrome?

TC Theoharides - Molecular Neurobiology, 2022 - Springer
SARS-CoV-2 infects cells via its spike protein binding to its surface receptor on target cells
and results in acute symptoms involving especially the lungs known as COVID-19. However …

Long‐COVID syndrome‐associated brain fog and chemofog: Luteolin to the rescue

TC Theoharides, C Cholevas, K Polyzoidis… - Biofactors, 2021 - Wiley Online Library
COVID‐19 leads to severe respiratory problems, but also to long‐COVID syndrome
associated primarily with cognitive dysfunction and fatigue. Long‐COVID syndrome …

[PDF][PDF] Be aware of SARS-CoV-2 spike protein: There is more than meets the eye

TC Theoharides, P Conti - J Biol Regul Homeost Agents, 2021 - mastcellmaster.com
The COVID-19 pandemic necessitated the rapid production of vaccines aimed at the
production of neutralizing antibodies against the COVID-19 spike protein required for the …

Real world research on transcranial magnetic stimulation treatment strategies for neuropsychiatric symptoms with long-COVID in Japan

Y Noda, A Sato, M Shichi, A Sato, K Fujii… - Asian Journal of …, 2023 - Elsevier
The number of patients suffering from long-COVID is currently increasing rapidly, even after
the acute symptoms of COVID-19 have improved. The objective of this study was to …

[HTML][HTML] Prognostic indicators and outcomes of hospitalised COVID-19 patients with neurological disease: An individual patient data meta-analysis

B Singh, S Lant, S Cividini, JWS Cattrall, LC Goodwin… - PLoS …, 2022 - journals.plos.org
Background Neurological COVID-19 disease has been reported widely, but published
studies often lack information on neurological outcomes and prognostic risk factors. We …

Recombinant SARS-CoV-2 Spike Protein and its Receptor Binding Domain stimulate release of different pro-inflammatory mediators via activation of distinct receptors …

I Tsilioni, TC Theoharides - Molecular Neurobiology, 2023 - Springer
SARS-CoV-2 infects cells via its spike (S) protein binding to its surface receptor angiotensin
converting enzyme 2 (ACE2) on target cells and results in acute symptoms involving …

Mast cells in the autonomic nervous system and potential role in disorders with dysautonomia and neuroinflammation

TC Theoharides, A Twahir, D Kempuraj - Annals of Allergy, Asthma & …, 2023 - Elsevier
Mast cells (MC) are ubiquitous in the body and are critical for allergic diseases, but also in
immunity and inflammation, as well as potential involvement in the pathophysiology of …

[HTML][HTML] Neuroimaging findings in patients with COVID-19: a systematic review and meta-analysis

PH Kim, M Kim, CH Suh, SR Chung… - Korean journal of …, 2021 - ncbi.nlm.nih.gov
Objective Central nervous system involvement in coronavirus disease 2019 (COVID-19) has
been increasingly reported. We performed a systematic review and meta-analysis to …

[HTML][HTML] Ways to address perinatal mast cell activation and focal brain inflammation, including response to SARS-CoV-2, in autism spectrum disorder

TC Theoharides - Journal of Personalized Medicine, 2021 - mdpi.com
The prevalence of autism spectrum disorder (ASD) continues to increase, but no distinct
pathogenesis or effective treatment are known yet. The presence of many comorbidities …

[HTML][HTML] Multi-organ system involvement in coronavirus disease 2019 (COVID-19): A mega review

N Moslehi, MH Jahromy, P Ashrafi… - Journal of Family …, 2022 - journals.lww.com
Since the pandemic of the coronavirus disease 2019 (COVID-19) infection, many people
have been affected in different ways. The majority of infected people experience mild to …