Mechanistic development and recent applications of the Chan–Lam amination

MJ West, JWB Fyfe, JC Vantourout… - Chemical …, 2019 - ACS Publications
Transition metal-mediated formation of C–N bonds is an essential synthetic methodology.
The discovery of the Chan–Lam amination provided a C–N bond forming process that was …

N‐Heteroarylation of Sulfonamides: An Overview

S Ghosh, PP Pal, A Hajra - Advanced Synthesis & Catalysis, 2023 - Wiley Online Library
N‐Heteroaryl sulfonamides are an extremely significant variety of organosulfur compounds
that are present in many significant FDA‐approved drugs and therapeutic agents. Therefore …

7-Azaindole N-Oxide (7-AINO) Mediated Cu-Catalyzed N-Arylation: Mechanistic Investigation into the Role of Fluoride Ions

K Mondal, N Mukhopadhyay, S Patra, T Roy… - ACS Catalysis, 2023 - ACS Publications
A Cu (II) fluoride-catalyzed N-arylation of 7-azaindole N-oxides (7-AINO) has been
developed using boronic acid under base-free conditions. During the process, a …

Cu‐Catalyzed coupling reactions of sulfonamides with (hetero) aryl chlorides/bromides

Q Li, L Xu, D Ma - Angewandte Chemie, 2022 - Wiley Online Library
Direct N‐arylation of sulfonamides is a very attractive approach for preparing
pharmaceutically important N‐(hetero) aryl sulfonamides because it avoids the potential …

Copper anchored on phosphorus gC 3 N 4 as a highly efficient photocatalyst for the synthesis of N-arylpyridin-2-amines

JQ Di, M Zhang, YX Chen, JX Wang, SS Geng… - Green …, 2021 - pubs.rsc.org
A heterogeneous photocatalyst based on copper modified phosphorus doped g-C3N4 (Cu/P-
CN) has been prepared and characterized. This recyclable catalyst exhibited high …

Sulfondiimidamides as new functional groups for synthetic and medicinal chemistry

ZX Zhang, MC Willis - Chem, 2022 - cell.com
Due to their three-dimensional structure, chemical and metabolic stability, polarity, and
hydrogen-bonding ability, sulfonamides occupy a privileged position among the functional …

Mediator-enabled electrocatalysis with ligandless copper for anaerobic Chan–Lam coupling reactions

BR Walker, S Manabe, AT Brusoe… - Journal of the American …, 2021 - ACS Publications
Simple copper salts serve as catalysts to effect C–X bond-forming reactions in some of the
most utilized transformations in synthesis, including the oxidative coupling of aryl boronic …

An Organocopper(III) Fluoride Triggering C−CF3 Bond Formation

D Joven‐Sancho, A Echeverri… - Angewandte …, 2024 - Wiley Online Library
Copper (III) fluorides are catalytically competent, yet elusive, intermediates in cross‐
coupling. The synthesis of [PPh4][CuIII (CF3) 3F](2), the first stable (isolable) CuIII− F, was …

[HTML][HTML] The power and accessibility of high-throughput methods for catalysis research

CL Allen, DC Leitch, MS Anson, MA Zajac - Nature Catalysis, 2019 - nature.com
Developing catalytic reactions for organic synthesis is the central goal of countless research
groups worldwide. High-throughput experimentation is invaluable for this pursuit, with the …

Autocatalytic photoredox Chan-Lam coupling of free diaryl sulfoximines with arylboronic acids

C Wang, H Zhang, LA Wells, T Liu, T Meng… - Nature …, 2021 - nature.com
N-Arylation of NH-sulfoximines represents an appealing approach to access N-aryl
sulfoximines, but has not been successfully applied to NH-diaryl sulfoximines. Herein, a …