Depression in young people
A Thapar, O Eyre, V Patel, D Brent - The Lancet, 2022 - thelancet.com
Depression rates in young people have risen sharply in the past decade, especially in
females, which is of concern because adolescence is a period of rapid social, emotional …
females, which is of concern because adolescence is a period of rapid social, emotional …
The multiple roles of life stress in metabolic disorders
The activation of stress-related neuroendocrine systems helps to maintain homeostasis, but
excessive stress can damage body functions. We review current evidence from basic …
excessive stress can damage body functions. We review current evidence from basic …
Neurobiology of early life adversity: A systematic review of meta-analyses towards an integrative account of its neurobiological trajectories to mental disorders
Y Hakamata, Y Suzuki, H Kobashikawa… - Frontiers in …, 2022 - Elsevier
Adverse childhood experiences (ACEs) may leave long-lasting neurobiological scars,
increasing the risk of developing mental disorders in later life. However, no review has …
increasing the risk of developing mental disorders in later life. However, no review has …
Genetic insights into human cortical organization and development through genome-wide analyses of 2,347 neuroimaging phenotypes
Our understanding of the genetics of the human cerebral cortex is limited both in terms of the
diversity and the anatomical granularity of brain structural phenotypes. Here we conducted a …
diversity and the anatomical granularity of brain structural phenotypes. Here we conducted a …
A genetically informed Registered Report on adverse childhood experiences and mental health
Children who experience adversities have an elevated risk of mental health problems.
However, the extent to which adverse childhood experiences (ACEs) cause mental health …
However, the extent to which adverse childhood experiences (ACEs) cause mental health …
Genetic correlates of phenotypic heterogeneity in autism
The substantial phenotypic heterogeneity in autism limits our understanding of its genetic
etiology. To address this gap, here we investigated genetic differences between autistic …
etiology. To address this gap, here we investigated genetic differences between autistic …
Intergenerational transmission of the effects of maternal exposure to childhood maltreatment in the USA: a retrospective cohort study
NK Moog, PD Cummings, KL Jackson… - The Lancet Public …, 2023 - thelancet.com
Background Childhood maltreatment is associated with adverse health outcomes and this
risk can be transmitted to the next generation. We aimed to investigate the association …
risk can be transmitted to the next generation. We aimed to investigate the association …
Epigenetics and ADHD: reflections on current knowledge, research priorities and translational potential
Attention-deficit/hyperactivity disorder (ADHD) is a common and debilitating
neurodevelopmental disorder influenced by both genetic and environmental factors …
neurodevelopmental disorder influenced by both genetic and environmental factors …
Depression, cardiometabolic disease, and their co-occurrence after childhood maltreatment: an individual participant data meta-analysis including over 200,000 …
C Souama, F Lamers, Y Milaneschi, CH Vinkers… - BMC medicine, 2023 - Springer
Background Childhood maltreatment is associated with depression and cardiometabolic
disease in adulthood. However, the relationships with these two diseases have so far only …
disease in adulthood. However, the relationships with these two diseases have so far only …