Neurodegenerative disorders, such as Alzheimer's disease, are a global public health
burden with poorly understood aetiology. Neuroinflammation and oxidative stress (OS) are …

Diabetes is a metabolic disorder affecting large percentage of population worldwide. NF-κβ
plays key role in pathogenesis of vascular complications of diabetes. Persistent …

It is only recently that the full importance of nuclear factor-κB (NF-κB) signalling to cancer
development has been understood. Although much attention has focused on the upstream …

The metastatic process in breast cancer is related to the expression of the epithelial-to-
mesenchymal transition transcription factors (EMT-TFs) SNAIL, SLUG, SIP1 and TWIST1 …

Nuclear Factor-kappa B (NF-κB) is a transcription factor family that regulates a large number
of genes that are involved in important physiological processes, including survival …

Ovarian cancer is the most lethal gynecologic malignancy in the United States, with an
estimated 22,530 new cases and 13,980 deaths in 2019. Recent studies have indicated that …

NF-κB transcription factors are critical regulators of innate and adaptive immunity and major
mediators of inflammatory signaling. The NF-κB signaling is dysregulated in a significant …

Common environmental pollutants and drugs encountered in everyday life can cause toxic
damage to the body through oxidative stress, inflammatory stimulation, induction of …

Several kinds of anticancer drugs are presently commercially accessible, but low efficacy,
solubility, and toxicity have reduced the overall therapeutic indices. Thus, the search for …

Cancer and inflammation are intimately linked due to specific oxidative processes in the
tumor microenvironment. Lipoxygenases are a versatile class of oxidative enzymes involved …