Rebuilding the damaged heart: mesenchymal stem cells, cell-based therapy, and engineered heart tissue

S Golpanian, A Wolf, KE Hatzistergos… - Physiological …, 2016 - journals.physiology.org
Mesenchymal stem cells (MSCs) are broadly distributed cells that retain postnatal capacity
for self-renewal and multilineage differentiation. MSCs evade immune detection, secrete an …

Conventional and recent trends of scaffolds fabrication: a superior mode for tissue engineering

IM Adel, MF ElMeligy, NA Elkasabgy - Pharmaceutics, 2022 - mdpi.com
Tissue regeneration is an auto-healing mechanism, initiating immediately following tissue
damage to restore normal tissue structure and function. This falls in line with survival instinct …

In vitro engineering of vascularized tissue surrogates

K Sakaguchi, T Shimizu, S Horaguchi, H Sekine… - Scientific reports, 2013 - nature.com
In vitro scaling up of bioengineered tissues is known to be limited by diffusion issues,
specifically a lack of vasculature. Here, we report a new strategy for preserving cell viability …

Bioglass activated skin tissue engineering constructs for wound healing

H Yu, J Peng, Y Xu, J Chang, H Li - ACS applied materials & …, 2016 - ACS Publications
Wound healing is a complicated process, and fibroblast is a major cell type that participates
in the process. Recent studies have shown that bioglass (BG) can stimulate fibroblasts to …

Cell sheet engineering: a unique nanotechnology for scaffold‐free tissue reconstruction with clinical applications in regenerative medicine

I Elloumi‐Hannachi, M Yamato… - Journal of internal …, 2010 - Wiley Online Library
Cell sheet technology (CST) is based on the use of thermoresponsive polymers, poly (N‐
isopropylacrylamide)(PIPAAm). The surface of PIPAAms is formulated in such a way as to …

Biodegradable collagen patch with covalently immobilized VEGF for myocardial repair

Y Miyagi, LLY Chiu, M Cimini, RD Weisel, M Radisic… - Biomaterials, 2011 - Elsevier
Vascularization of engineered tissues in vitro and in vivo remains a key problem in
translation of engineered tissues to clinical practice. Growth factor signalling can be …

Human adult stem cells from diverse origins: an overview from multiparametric immunophenotyping to clinical applications

BR Sousa, RC Parreira, EA Fonseca… - Cytometry Part …, 2014 - Wiley Online Library
Stem cells are known for their capacity to self‐renew and differentiate into at least one
specialized cell type. Mesenchymal stem cells (MSCs) were isolated initially from bone …

[HTML][HTML] Adipose-derived stem cells: current findings and future perspectives

M Tobita, H Orbay, H Mizuno - Discovery medicine, 2011 - discoverymedicine.com
Adipose tissue is an abundant source of mesenchymal stem cells, which have shown
promise in the field of regenerative medicine. Furthermore, these cells can be readily …

Emergence of scaffold-free approaches for tissue engineering musculoskeletal cartilages

GD DuRaine, WE Brown, JC Hu… - Annals of biomedical …, 2015 - Springer
This review explores scaffold-free methods as an additional paradigm for tissue
engineering. Musculoskeletal cartilages—for example articular cartilage, meniscus …

Biomaterializing the promise of cardiac tissue engineering

JE Pomeroy, A Helfer, N Bursac - Biotechnology advances, 2020 - Elsevier
During an average individual's lifespan, the human heart pumps nearly 200 million liters of
blood delivered by approximately 3 billion heartbeats. Therefore, it is not surprising that …