Microfluidic devices: a tool for nanoparticle synthesis and performance evaluation
The use of nanoparticles (NPs) in nanomedicine holds great promise for the treatment of
diseases for which conventional therapies present serious limitations. Additionally, NPs can …
diseases for which conventional therapies present serious limitations. Additionally, NPs can …
Liposomes: Advancements and innovation in the manufacturing process
Liposomes are well recognised as effective drug delivery systems, with a range of products
approved, including follow on generic products. Current manufacturing processes used to …
approved, including follow on generic products. Current manufacturing processes used to …
[HTML][HTML] Microfluidic vortex focusing for high throughput synthesis of size-tunable liposomes
Control over vesicle size during nanoscale liposome synthesis is critical for defining the
pharmaceutical properties of liposomal nanomedicines. Microfluidic technologies capable of …
pharmaceutical properties of liposomal nanomedicines. Microfluidic technologies capable of …
[HTML][HTML] Microfluidic synthesis of highly potent limit-size lipid nanoparticles for in vivo delivery of siRNA
NM Belliveau, J Huft, PJC Lin, S Chen… - … Therapy-Nucleic Acids, 2012 - cell.com
Lipid nanoparticles (LNP) are the leading systems for in vivo delivery of small interfering
RNA (siRNA) for therapeutic applications. Formulation of LNP siRNA systems requires rapid …
RNA (siRNA) for therapeutic applications. Formulation of LNP siRNA systems requires rapid …
Liposomes for delivery of antioxidants in cosmeceuticals: Challenges and development strategies
V Van Tran, JY Moon, YC Lee - Journal of controlled release, 2019 - Elsevier
Antioxidants (AOs) play a crucial role in the protection and maintenance of health and are
also integral ingredients in beauty products. Unfortunately, most of them are sensitive due to …
also integral ingredients in beauty products. Unfortunately, most of them are sensitive due to …
Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation
The discovery of potent new materials for in vivo delivery of nucleic acids depends upon
successful formulation of the active molecules into a dosage form suitable for the …
successful formulation of the active molecules into a dosage form suitable for the …
[HTML][HTML] A review on microfluidic-assisted nanoparticle synthesis, and their applications using multiscale simulation methods
Recent years have witnessed an increased interest in the development of nanoparticles
(NPs) owing to their potential use in a wide variety of biomedical applications, including drug …
(NPs) owing to their potential use in a wide variety of biomedical applications, including drug …
Microfluidic and lab-on-a-chip preparation routes for organic nanoparticles and vesicular systems for nanomedicine applications
In recent years, advancements in the fields of microfluidic and lab-on-a-chip technologies
have provided unique opportunities for the implementation of nanomaterial production …
have provided unique opportunities for the implementation of nanomaterial production …
Characterization of lipid nanoparticles containing ionizable cationic lipids using design-of-experiments approach
T Terada, JA Kulkarni, A Huynh, S Chen… - Langmuir, 2021 - ACS Publications
Lipid nanoparticles (LNPs) containing short-interfering RNA (LNP-siRNA systems) are a
promising approach for silencing disease-causing genes in hepatocytes following …
promising approach for silencing disease-causing genes in hepatocytes following …
Microfluidics based manufacture of liposomes simultaneously entrapping hydrophilic and lipophilic drugs
S Joshi, MT Hussain, CB Roces, G Anderluzzi… - International journal of …, 2016 - Elsevier
Despite the substantial body of research investigating the use of liposomes, niosomes and
other bilayer vesicles for drug delivery, the translation of these systems into licensed …
other bilayer vesicles for drug delivery, the translation of these systems into licensed …