Multimodal analgesia, current concepts, and acute pain considerations

EM Helander, BL Menard, CM Harmon… - Current pain and …, 2017 - Springer
Abstract Purpose of Review Management of acute pain following surgery using a multimodal
approach is recommended by the American Society of Anesthesiologists whenever …

Geriatric physiology and the frailty syndrome

KT Khan, K Hemati… - Anesthesiology …, 2019 - anesthesiology.theclinics.com
The prevalence of older adults undergoing surgery is expected to increase as the population
ages. 1 Because of physiologic decline and loss of functional reserve, older patients are at a …

Ketamine triggers a switch in excitatory neuronal activity across neocortex

J Cichon, AZ Wasilczuk, LL Looger, D Contreras… - Nature …, 2023 - nature.com
The brain can become transiently disconnected from the environment while maintaining
vivid, internally generated experiences. This so-called 'dissociated state'can occur in …

Effects of intraoperative fluid management on postoperative outcomes: a hospital registry study

CH Shin, DR Long, D McLean, SD Grabitz… - Annals of …, 2018 - journals.lww.com
Objective: Evaluate the dose-response relationship between intraoperative fluid
administration and postoperative outcomes in a large cohort of surgical patients …

Driving pressure during thoracic surgery: a randomized clinical trial

MH Park, HJ Ahn, JA Kim, M Yang, BY Heo… - …, 2019 - pubs.asahq.org
Abstract Editor's Perspective What We Already Know about This Topic Driving pressure
(plateau minus end-expiratory airway pressure) is a target in patients with acute respiratory …

Optogenetic activation of dopamine neurons in the ventral tegmental area induces reanimation from general anesthesia

NE Taylor, CJ Van Dort, JD Kenny… - Proceedings of the …, 2016 - National Acad Sciences
Dopamine (DA) promotes wakefulness, and DA transporter inhibitors such as
dextroamphetamine and methylphenidate are effective for increasing arousal and inducing …

An open source patient simulator for design and evaluation of computer based multiple drug dosing control for anesthetic and hemodynamic variables

CM Ionescu, M Neckebroek, M Ghita, D Copot - IEEE Access, 2021 - ieeexplore.ieee.org
We are witnessing a notable rise in the translational use of information technology and
control systems engineering tools in clinical practice. This paper empowers the computer …

[HTML][HTML] Capturing emotion reactivity through physiology measurement as a foundation for affective engineering in engineering design science and engineering …

S Balters, M Steinert - Journal of Intelligent Manufacturing, 2017 - Springer
This paper presents the theoretical and practical fundamentals of using physiology sensors
to capture human emotion reactivity in a products or systems engineering context. We aim to …

Opioid overdose detection using smartphones

R Nandakumar, S Gollakota, JE Sunshine - Science translational …, 2019 - science.org
Early detection and rapid intervention can prevent death from opioid overdose. At high
doses, opioids (particularly fentanyl) can cause rapid cessation of breathing (apnea) …

[HTML][HTML] Association between intraoperative opioid administration and 30-day readmission: a pre-specified analysis of registry data from a healthcare network in New …

DR Long, AL Lihn, S Friedrich… - British journal of …, 2018 - Elsevier
Background The use of intraoperative opioids may influence the rate of postoperative
complications. This study evaluated the association between intraoperative opioid dose and …