Over the past three decades of intense research on the contribution of viral and host factors
determining the variability in HIV-1 infection outcome, HIV pathogenesis is still a fascinating …

The envelope glycoprotein complex of replication competent retroviruses is comprised of
two polypeptides, an external, glycosylated, hydrophilic polypeptide (SU) and a membrane …

Chronic myelogenous leukemia (CML) is a human disease associated with a consistent
chromosomal translocation that results in sequences from the c-abl locus on chromosome 9 …

Human T-lymphotropic virus type III (HTLV-III) or lymphadenopathy-associated virus (LAV) is
tropic for human T cells with the helper-inducer phenotype, as defined by reactivity with …

To determine the extent and nature of genetic variation present in independent isolates of
HTLV-IIIILAV, the nucleotlde sequences of the entire envelope gene and parts of gag and …

Adhesive interactions of the platelet surface with plasma proteins such as fibrinogen and
fibronectin play an important role in thrombosis and hemostasis. The binding of both of these …

Antibodies from the serum of patients with the acquired immune deficiency syndrome (AIDS)
or with the AIDS-related complex and from the serum of seropositive healthy homosexuals …

The envelope of the human immunodeficiency virus type 1 (HIV-1) plays a central role in the
process of virus entry into the host cell and in the cytopathicity of the virus for lymphocytes …

The trans-activator gene (tat-Ill) of the human T lymphotropic virus type Ill (HTLV-IIIILAV) is
shown to regulate positively the expression of viral proteins. Viruses in which the fat-Ill gene …

The primary event in the infection of cells by HIV is the interaction between the viral
envelope glycoprotein, gp120, and its cellular receptor, CD4. A recombinant form of gp120 …