From mechanisms to markers: novel noninvasive EEG proxy markers of the neural excitation and inhibition system in humans
Brain function is a product of the balance between excitatory and inhibitory (E/I) brain
activity. Variation in the regulation of this activity is thought to give rise to normal variation in …
activity. Variation in the regulation of this activity is thought to give rise to normal variation in …
Efficient codes and balanced networks
S Denève, CK Machens - Nature neuroscience, 2016 - nature.com
Recent years have seen a growing interest in inhibitory interneurons and their circuits. A
striking property of cortical inhibition is how tightly it balances excitation. Inhibitory currents …
striking property of cortical inhibition is how tightly it balances excitation. Inhibitory currents …
Discrete attractor dynamics underlies persistent activity in the frontal cortex
Short-term memories link events separated in time, such as past sensation and future
actions. Short-term memories are correlated with slow neural dynamics, including selective …
actions. Short-term memories are correlated with slow neural dynamics, including selective …
Equalizing excitation–inhibition ratios across visual cortical neurons
M Xue, BV Atallah, M Scanziani - Nature, 2014 - nature.com
The relationship between synaptic excitation and inhibition (E/I ratio), two opposing forces in
the mammalian cerebral cortex, affects many cortical functions such as feature selectivity …
the mammalian cerebral cortex, affects many cortical functions such as feature selectivity …
Normalization as a canonical neural computation
M Carandini, DJ Heeger - Nature reviews neuroscience, 2012 - nature.com
There is increasing evidence that the brain relies on a set of canonical neural computations,
repeating them across brain regions and modalities to apply similar operations to different …
repeating them across brain regions and modalities to apply similar operations to different …
Single-neuron perturbations reveal feature-specific competition in V1
SN Chettih, CD Harvey - Nature, 2019 - nature.com
The computations performed by local neural populations, such as a cortical layer, are
typically inferred from anatomical connectivity and observations of neural activity. Here we …
typically inferred from anatomical connectivity and observations of neural activity. Here we …
Neurophysiological and computational principles of cortical rhythms in cognition
XJ Wang - Physiological reviews, 2010 - journals.physiology.org
Synchronous rhythms represent a core mechanism for sculpting temporal coordination of
neural activity in the brain-wide network. This review focuses on oscillations in the cerebral …
neural activity in the brain-wide network. This review focuses on oscillations in the cerebral …
[HTML][HTML] How inhibition shapes cortical activity
JS Isaacson, M Scanziani - Neuron, 2011 - cell.com
Cortical processing reflects the interplay of synaptic excitation and synaptic inhibition.
Rapidly accumulating evidence is highlighting the crucial role of inhibition in shaping …
Rapidly accumulating evidence is highlighting the crucial role of inhibition in shaping …
The logic of recurrent circuits in the primary visual cortex
Recurrent cortical activity sculpts visual perception by refining, amplifying or suppressing
visual input. However, the rules that govern the influence of recurrent activity remain …
visual input. However, the rules that govern the influence of recurrent activity remain …
Parvalbumin-expressing interneurons linearly transform cortical responses to visual stimuli
BV Atallah, W Bruns, M Carandini, M Scanziani - Neuron, 2012 - cell.com
The response of cortical neurons to a sensory stimulus is shaped by the network in which
they are embedded. Here we establish a role of parvalbumin (PV)-expressing cells, a large …
they are embedded. Here we establish a role of parvalbumin (PV)-expressing cells, a large …