Brain function is a product of the balance between excitatory and inhibitory (E/I) brain
activity. Variation in the regulation of this activity is thought to give rise to normal variation in …

Recent years have seen a growing interest in inhibitory interneurons and their circuits. A
striking property of cortical inhibition is how tightly it balances excitation. Inhibitory currents …

Short-term memories link events separated in time, such as past sensation and future
actions. Short-term memories are correlated with slow neural dynamics, including selective …

The relationship between synaptic excitation and inhibition (E/I ratio), two opposing forces in
the mammalian cerebral cortex, affects many cortical functions such as feature selectivity …

There is increasing evidence that the brain relies on a set of canonical neural computations,
repeating them across brain regions and modalities to apply similar operations to different …

The computations performed by local neural populations, such as a cortical layer, are
typically inferred from anatomical connectivity and observations of neural activity. Here we …

Synchronous rhythms represent a core mechanism for sculpting temporal coordination of
neural activity in the brain-wide network. This review focuses on oscillations in the cerebral …

Cortical processing reflects the interplay of synaptic excitation and synaptic inhibition.
Rapidly accumulating evidence is highlighting the crucial role of inhibition in shaping …

Recurrent cortical activity sculpts visual perception by refining, amplifying or suppressing
visual input. However, the rules that govern the influence of recurrent activity remain …

The response of cortical neurons to a sensory stimulus is shaped by the network in which
they are embedded. Here we establish a role of parvalbumin (PV)-expressing cells, a large …