Apical periodontitis caused by root canal infection is the most frequent pathological lesion in
the jaws, mainly manifested as periapical granulomas and cysts. Understanding of the …

With the pandemic of COVID-19, maintenance of oral health has increasingly become the
main challenge of global health. Various common oral diseases, such as periodontitis and …

Objective This study aimed to investigate the use of texture analysis for characterization of
radicular cysts and periapical granulomas and to assess its efficacy to differentiate between …

Objective: This study evaluated the expression of pro-inflammatory (IL-1β, IL-6, IFN-γ and
TNF-α) and anti-inflammatory (IL-4 and TGF-β) cytokines in apical periodontitis lesions …

Apical periodontitis (AP) is a chronic inflammatory disease characterized by periapical tissue
inflammation and destruction of the associated alveolar bone. It is caused by microbial …

The process involved in periapical lesions, which occur as an outcome of pulpal necrosis, is
regulated by the immune system including regulatory T cells (Treg) and T helper 17 cell …

Inflammatory radicular cysts (IRCs) are chronic lesions that follow the development of
periapical granulomas (PGs). IRCs result from multiple inflammatory reactions led initially by …

Abstract Introduction Interleukin (IL)-17 expression has been detected in apical periodontitis
lesions, but its role in the disease process remains unclear. The present study compared the …

Apical periodontitis (AP) is a prevalent infectious and inflammatory disorder that involves
inflammation of periapical tissues and the disintegration of alveolar bone. AP may eventually …

Introduction The pathogenesis of periapical lesions is determined by the balance between
host proinflammatory immune response and counteracting anti-inflammatory and reparative …