Biologists have long appreciated the critical role that energy turnover plays in understanding
variation in performance and fitness among individuals. Whole-organism metabolic studies …

Oxidative stress occurs when the levels of reactive oxygen species (ROS) overcome the
antioxidant defenses of the organism, jeopardizing several biological functions, including …

The widespread use of silica nanoparticles (SiO 2-NPs) in various industries, including
chemical polishing, cosmetics, varnishes, medical, and food products, has increased the risk …

Human activity is changing climatic conditions at an unprecedented rate. The impact of
these changes may be especially acute on ectotherms since they have limited capacities to …

Oxidative stress is the subject of numerous studies, most of them focusing on the negative
effects exerted at both molecular and cellular levels, ignoring the possible benefits of free …

Kidney fibrosis is associated with tubular injury, oxidative stress and activation of interstitial
fibroblasts. However, whether these events are somehow connected is poorly understood. In …

Species persistence in the Anthropocene is dramatically threatened by global climate
change. Large emissions of carbon dioxide (CO 2) from human activities are driving …

Climate change is causing increases in temperature and in the frequency of extreme
weather events. Under this scenario, organisms should maintain or develop strategies to …

Oxidative stress is a major cause of morbidity and mortality in human health and disease. In
this review, we focus on the Forkhead Box (Fox) subclass O3 (FoxO3), an extensively …

Stress is ubiquitous and thus, not surprisingly, many hypotheses and models have been
created to better study the role stress plays in life. Stress spans fields and is found in the …