Zinc metabolism and metallothioneins

AK Baltaci, K Yuce, R Mogulkoc - Biological trace element research, 2018 - Springer
Among the trace elements, zinc is one of the most used elements in biological systems. Zinc
is found in the structure of more than 2700 enzymes, including hydrolases, transferases …

The cardiotoxicity of the common carp (Cyprinus carpio) exposed to environmentally relevant concentrations of arsenic and subsequently relieved by zinc …

H Zhao, Y Wang, J Liu, M Guo, D Fei, H Yu… - Environmental Pollution, 2019 - Elsevier
Waterborne exposure to arsenic trioxide (As 2 O 3) is inevitable due to its widespread
industrial and agricultural applications. Oxidative stress and cascaded programmed cell …

Zinc: Roles in pancreatic physiology and disease

M Wang, M Phadke, D Packard, D Yadav, F Gorelick - Pancreatology, 2020 - Elsevier
Zinc is an essential trace element. Deficiencies are frequently seen with gastrointestinal
diseases, including chronic pancreatitis, nutritional deficiency, and reduced intestinal …

In vitro Antiproliferative and Apoptosis Inducing Effect of Allium atroviolaceum Bulb Extract on Breast, Cervical, and Liver Cancer Cells

S Khazaei, NM Esa, V Ramachandran… - Frontiers in …, 2017 - frontiersin.org
Natural products are considered potent sources for novel drug discovery and development.
The multiple therapeutic effects of natural compounds in traditional medicine motivate us to …

[HTML][HTML] Zinc/alogliptin combination attenuates testicular toxicity induced by doxorubicin in rats: Role of oxidative stress, apoptosis and TGF-β1/NF-κB signaling

AM Kabel - Biomedicine & Pharmacotherapy, 2018 - Elsevier
The aim of this study was to assess the effect of alogliptin and/or zinc on doxorubicin (DOX)-
induced testicular toxicity in rats. Sixty male Wistar rats were divided into 6 equal groups …

Schiff base as a fluorescent sensor derived from chromone moiety for the effective detection of Zn (II) ions

N Tomer, R Malhotra - Journal of Molecular Structure, 2022 - Elsevier
Abstract A new Schiff base 5-[(4-Oxo-4H-chromen-3-ylmethylene)-amino]-1H-pyrimidine-2,
4‑dione (CUR) was synthesized from chromone moiety and identified as a colorimetric as …

Synthesis and biological evaluation of indole-2-carboxamides with potent apoptotic antiproliferative activity as egfr/cdk2 dual inhibitors

LH Al-Wahaibi, YA Mostafa, MH Abdelrahman… - Pharmaceuticals, 2022 - mdpi.com
The apoptotic antiproliferative actions of our previously reported CB1 allosteric modulators 5-
chlorobenzofuran-2-carboxamide derivatives VIIa–j prompted us to develop and synthesise …

[HTML][HTML] Flurochloridone induces Sertoli cell apoptosis through ROS-dependent mitochondrial pathway

W Sun, Z Ni, R Li, X Chang, W Li, M Yang… - … and environmental safety, 2021 - Elsevier
Flurochloridone (FLC), a selective herbicide used on a global scale, has been reported to
have male reproductive toxicity which underlying mechanism is still largely unknown. The …

Zinc enhances the cellular energy supply to improve cell motility and restore impaired energetic metabolism in a toxic environment induced by OTA

X Yang, H Wang, C Huang, X He, W Xu, Y Luo… - Scientific reports, 2017 - nature.com
Exogenous nutrient elements modulate the energetic metabolism responses that are
prerequisites for cellular homeostasis and metabolic physiology. Although zinc is important …

Soy isoflavones improve the spermatogenic defects in diet-induced obesity rats through Nrf2/HO-1 pathway

Q Luo, Y Li, C Huang, D Cheng, W Ma, Y Xia, W Liu… - Molecules, 2019 - mdpi.com
Soy isoflavones (SIF) are biologically active compounds of non-steroidal and phenolic
properties that are richly present in soybeans, which can reduce the body weight and blood …