2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery …
G Hindricks, T Potpara, N Dagres, E Arbelo… - European heart …, 2021 - academic.oup.com
MicroRNAs (miRNAs) are small regulatory molecules post-transcriptionally suppressing
mRNA activity. Many miRNAs in various organisms have been cloned but many unknown …
mRNA activity. Many miRNAs in various organisms have been cloned but many unknown …
Insights into mechanisms of GDF15 and receptor GFRAL: therapeutic targets
L Rochette, M Zeller, Y Cottin, C Vergely - Trends in Endocrinology & …, 2020 - cell.com
Growth and differentiation factor 15 (GDF15) belongs to the transforming growth factor-β
(TGF-β) superfamily proteins. GDF15 acts as an inflammatory marker, and it plays a role in …
(TGF-β) superfamily proteins. GDF15 acts as an inflammatory marker, and it plays a role in …
Antithrombotic therapy for atrial fibrillation: CHEST guideline and expert panel report
Background The risk of stroke is heterogeneous across different groups of patients with atrial
fibrillation (AF), being dependent on the presence of various stroke risk factors. We provide …
fibrillation (AF), being dependent on the presence of various stroke risk factors. We provide …
Incident risk factors and major bleeding in patients with atrial fibrillation treated with oral anticoagulants: a comparison of baseline, follow-up and delta HAS-BLED …
Aim When assessing bleeding risk in patients with atrial fibrillation (AF), risk stratification is
often based on the baseline risks. We aimed to investigate changes in bleeding risk factors …
often based on the baseline risks. We aimed to investigate changes in bleeding risk factors …
The prothrombotic state in atrial fibrillation: pathophysiological and management implications
AA Khan, GYH Lip - Cardiovascular research, 2019 - academic.oup.com
Atrial fibrillation (AF) is the commonest sustained cardiac arrhythmia and is associated with
significant morbidity and mortality. There is plenty of evidence available to support the …
significant morbidity and mortality. There is plenty of evidence available to support the …
A novel biosensing platform for detection of glaucoma biomarker GDF15 via an integrated BLI-ELASA strategy
S Gao, Q Li, S Zhang, X Sun, H Zhou, Z Wang, J Wu - Biomaterials, 2023 - Elsevier
Highlights•An aptamer with high affinity, high specificity, and high stability for binding to both
human-derived and rat-derived GDF15 was obtained.• The molecular mechanism and key …
human-derived and rat-derived GDF15 was obtained.• The molecular mechanism and key …
The use of biomarkers in clinical management guidelines: a critical appraisal
MA Esteve-Pastor, V Roldan… - Thrombosis and …, 2019 - thieme-connect.com
In cardiovascular disease (CVD), biomarkers (ie,“biological markers”) could have multiple
roles in understanding the complexity of cardiovascular (CV) pathophysiology and to offer …
roles in understanding the complexity of cardiovascular (CV) pathophysiology and to offer …
Long-term bleeding risk prediction in 'real world'patients with atrial fibrillation: comparison of the HAS-BLED and ABC-Bleeding risk scores
MA Esteve-Pastor, JM Rivera-Caravaca… - Thrombosis and …, 2017 - thieme-connect.com
Risk scores in patients with atrial fibrillation (AF) based on clinical factors alone generally
have only modest predictive value for predicting high risk patients that sustain events …
have only modest predictive value for predicting high risk patients that sustain events …
Assessment and mitigation of bleeding risk in atrial fibrillation and venous thromboembolism: A Position Paper from the ESC Working Group on Thrombosis, in …
Whilst there is a clear clinical benefit of oral anticoagulation (OAC) in patients with atrial
fibrillation (AF) and venous thromboembolism (VTE) in reducing the risks of …
fibrillation (AF) and venous thromboembolism (VTE) in reducing the risks of …
Human retinal organoids provide a suitable tool for toxicological investigations: a comprehensive validation using drugs and compounds affecting the retina
B Dorgau, M Georgiou, A Chaudhary… - Stem Cells …, 2022 - academic.oup.com
Retinal drug toxicity screening is essential for the development of safe treatment strategies
for a large number of diseases. To this end, retinal organoids derived from human …
for a large number of diseases. To this end, retinal organoids derived from human …