Neurological disorders represent major health concerns in terms of comorbidity and
mortality worldwide. Despite a tremendous increase in our understanding of the …

Tissue factor pathway inhibitor-2 (TFPI-2), a member of the Kunitz-type serine proteinase
inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). The …

The transcription factor Forkhead box M1 (FoxM1) is overexpressed in malignant glioma.
However, the functional importance of this factor in human glioma is not known. In the …

Using microarrays, we have screened for genes reactivated by drugs that modify epigenetic
mechanisms in pancreatic cancer cells. One of the genes identified was tissue factor …

Clotting activation occurs frequently in cancer. Tissue factor (TF), the most potent initiator of
coagulation, is expressed aberrantly in many types of malignancy and is involved not only in …

Expression of microRNA genes is profoundly altered in cancer but their role in the
development of androgen-independent prostate cancer has received limited attention as yet …

Tissue factor pathway inhibitor-2 (TFPI-2) is a Kunitz-type serine proteinase inhibitor that
inhibits plasmin-dependent activation of several metalloproteinases. Downregulation of TFPI …

Invasion of tumor cells is the primary cause of therapeutic failure in the treatment of
malignant gliomas. In an attempt to investigate the properties of the malignant progression of …

The progression of neoplasms is frequently associated with thromboembolic complications.
Coagulation proteins, particularly tissue factor (TF), have been shown to play a role in tumor …

Tissue factor pathway inhibitor 2 (TFPI-2) is a 32-kDa extracellular matrix-associated kunitz-
type serine proteinase inhibitor. It is secreted by all vascular cells and plays a role in tumor …